Results 101 to 110 of about 51,633,057 (277)

Type 6 Design L Starboard Side

open access: yes, 1918
Print no.
Navy Dept. Bureau of C&R, Washington D.C.   +1 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade

open access: yesJournal of Neuroscience, 2000
In spite of the recognition that striatal D2 receptors are critical determinants in a variety of psychomotor disorders, the cellular mechanisms by which these receptors shape neuronal activity have remained a mystery.
S. Hernández-López   +6 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Functional diversity of L-type calcium channels in rat cerebellar neurons

open access: yes, 1993
Single-channel recordings show that functionally different L-type Ca2+ channels coexist in rat cerebellar granules. Besides two different dihydropyridine (DHP)sensitive gating patterns with properties similar to those of cardiac L-type channels ...
forti L., Pietrobon D.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Type 3 Design L Starboard Side

open access: yes, 1918
red pencil 09https://digitalcommons.risd.edu/dazzleprints/1082/thumbnail ...
Navy Dept. Bureau of C&R, Washington D.C.   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

فراح غالي الصالحي تاثير مستوى الهيموغلوبين المسكر وفرط الاكسدة في مرشى السكري

open access: yesمجلة علوم ذي قار, 2019
This study was performed on (85) diabetic patients , classified as follows : 43 patients of type I (25 male and 18 femels) and 42 patients of type II (24 males and 18 femels .In addition , 55 healthy subjects were investigated as a control group.
فراح غالي
doaj  

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