Results 11 to 20 of about 51,633,057 (277)

CardiacModelling/L-type-Ca-rundown-experiments: v1.01

open access: yes, 2023
<p>Code and data associated with the paper "Investigation of the contribution of sub-membrane calcium to rundown of the L-type calcium current", now including licence file.</p ...
Gary Mirams, Aditi Agrawal
core   +1 more source

CardiacModelling/L-type-Ca-rundown-experiments: v1.0

open access: yes, 2023
<p>Data and code associated with the paper "Investigation of the contribution of sub-membrane calcium to rundown of the L-type calcium current" by Aditi Agrawal et al.
Gary Mirams, Aditi Agrawal
core   +1 more source

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil

open access: yesPharmaceutical Biology, 2022
Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański   +9 more
doaj   +1 more source

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

open access: yesNature Communications, 2016
Mounting in vitro, in vivo and clinical evidence suggest an important role for filopodia in driving cancer cell invasion. Using a high-throughput microscopic-based drug screen, we identify FDA-approved calcium channel blockers (CCBs) as potent inhibitors
Guillaume Jacquemet   +10 more
semanticscholar   +1 more source

L-type voltage-operated calcium channels contribute to astrocyte activation in vitro

open access: yesGlia, 2016
We have found a significant upregulation of L‐type voltage‐operated Ca++ channels (VOCCs) in reactive astrocytes. To test if VOCCs are centrally involved in triggering astrocyte reactivity, we used in vitro models of astrocyte activation in combination ...
Veronica T. Cheli   +5 more
semanticscholar   +1 more source

High resolution melting curve analysis revealed SNPs in major cannabinoid genes associated with drug and non-drug types of cannabis

open access: yesBiotechnology & Biotechnological Equipment, 2017
Cannabis sativa L. has a long history of cultivation as food, fibre, medicine and recreational drugs. Production of high tetrahydrocannabinol (THC) plants for narcotic use (drug type) is illegal and under control in most countries.
Tahereh Borna   +2 more
doaj   +1 more source

Heterologous expression, purification and characterization of L-type lectin homologue from Leishmania donovani

open access: yesBiotechnology Reports, 2015
Leishmaniasis, a disease of the developing world affects about 12 million people and has limited therapeutic interventions available. L-type lectins, Endoplasmic Reticulum Golgi Intermediate Compartment/Vesicular Integral Proteins (ERGIC-53/VIP36) are ...
Vijay Singh   +5 more
doaj   +1 more source

Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

open access: yesCurrent Molecular Pharmacology, 2015
Inhibition of voltage-gated L-type calcium channels by organic calcium channel blockers is a well-established pharmacodynamic concept for the treatment of hypertension and cardiac ischemia.
J. Striessnig   +2 more
semanticscholar   +1 more source

Rate preservation of double sequences under l-l type transformation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
Following the concepts of divergent rate preservation for ordinary sequences, we present a notion of rates preservation of divergent double sequences under l-l type transformations.
Richard F. Patterson
doaj   +1 more source

Hardy type inequalities in L p $L^{p}$ with sharp remainders

open access: yesJournal of Inequalities and Applications, 2017
Sharp remainder terms are explicitly given on the standard Hardy inequalities in L p ( R n ) $L^{p}(\mathbb {R}^{n})$ with 1 < p < n $1< p< n$ . Those remainder terms provide a direct and exact understanding of Hardy type inequalities in the framework of
Norisuke Ioku   +2 more
doaj   +1 more source

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