Results 251 to 260 of about 51,633,057 (277)

Biphasic effects on human atrial arrhythmogenicity of L-type calcium channel mutations associated with a Brugada/Short QT overlap syndrome - insights from a multiscale simulation study. [PDF]

PLoS Comput Biol
Xiang Y, Hancox JC, Zhang H.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Amniotic fluid neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein levels in predicting long-term prognosis in fetal growth restriction and preterm birth: a preliminary study. [PDF]

Front Pediatr
Katsura D, Tsuji S, Tokoro S, Inatomi A, Kita N, Murakami T.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

L-type association between magnesium intake and human papillomavirus infection in US adult women: based on NHANES 2003-2016 data. [PDF]

Front Nutr
Chen H, Chen X, Chen Y, Tang L, Shi WJ, Ou YH.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Amlodipine, an L-type Ca2+ channel inhibitor, regulates release of extracellular vesicles from tumor cells. [PDF]

Carcinogenesis
Mondal SK, Hong CS, Han J, Diergaarde B, Zandberg DP, Whiteside TL.   +5 more
europepmc   +1 more source

The calcium transient coupled to the L-type calcium current attenuates cardiac alternans. [PDF]

Front Physiol
Warren M, Poelzing S.
europepmc   +1 more source

A Better Understanding of Atrial-like and Ventricular-like Action Potentials in Stem Cell-Derived Cardiomyocytes: The Underestimated Role of the L-Type Ca²⁺ Current. [PDF]

Cells
Verkerk AO, Veerman CC, Hoekstra M, Devalla HD, Wilders R.   +4 more
europepmc   +1 more source

A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings. [PDF]

Sci Adv
Del Rivero Morfin PJ, Chavez DS, Jayaraman S, Yang L, Geisler SM, Kochiss AL, Tuluc P, Colecraft HM, Marx SO, Liu XS, Rajadhyaksha AM, Ben-Johny M.   +11 more
europepmc   +1 more source