Results 111 to 120 of about 22,320 (225)

Peptide-based inhibitors targeting the PD-1/PD-L1 axis: potential immunotherapeutics for cancer

Translational Oncology
The PD-1/PD-L1 complex belongs to the group of inhibitory immune checkpoints and plays a critical role in immune regulation. The PD-1/PD-L1 axis is also responsible for immune evasion of cancer cells, and this complex is one of the main targets of ...
Magdalena Bojko, Katarzyna Węgrzyn, Emilia Sikorska, Piotr Ciura, Claire Battin, Peter Steinberger, Katarzyna Magiera-Mularz, Grzegorz Dubin, Adam Kulesza, Adam K. Sieradzan, Marta Spodzieja, Sylwia Rodziewicz-Motowidło   +11 more
doaj   +1 more source

Activated Ras induces a normal p53 response but does not up-regulate ribosomal protein L11.

, 2013
A. Detection of L11 and β-actin by immunoblot analysis of total cellular lysate prepared from the indicated mouse karatinocyte cell lines. β-actin serves as a loading control. B.
Yanping Zhang (153797), Wenqi Pan (348953), Sameer Issaq (348954)   +2 more
core   +1 more source

Category management for the operational resource procurement

Journal of Innovation & Knowledge
The introduction of Category Management in operational resources purchasing helps to improve logistics service levels and increase the profitability of industrial enterprises. There are two main purposes of the provided article.
Ivan Elyashevich, Victor Sergeev, Valentina Dybskaya, Anastasia Ivanova   +3 more
doaj   +1 more source

Lapa do Santo unit L11 at level 10.

, 2015
a) Field picture. The black arrow points to the block that marks the upper limit of the pit of Burial 26; b) schematic representation of Unit L11’s level 10, the black contours indicate the approximate limit of each burial.
Rodrigo Elias Oliveira (799262), Renato Kipnis (182418), Domingo C. Salazar-García (799263), Sahra Talamo (116803), Klervia Jaouen (618696), Caroline Wilkinson (130646), Astolfo G. M. Araujo (182411), Danilo V. Bernardo (182414), Michael Phillip Richards (799264), Mark Hubbe (247586), Walter Alves Neves (799265), André Strauss (799261), Sue Black (3328782)   +12 more
core   +1 more source

Translational regulation via L11: Molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

, 2008
The thiopeptide class of antibiotics targets the GTPase-associated center (GAC) of the ribosome to inhibit translation factor function. Using X-ray crystallography, we have determined the binding sites of thiostrepton (Thio), nosiheptide (Nosi), and ...
Wilson, D. N., Stachelhaus, T., Schluenzen, F., Connell, S. R., Spahn, C. M. T., M Harms, J., Fucini, P., Zaborowska, Z.   +7 more
core   +1 more source

Concentración de mercados, colusión y bienestar social en México. Una revisión metodológica

El Trimestre Económico, 2016
En este artículo se presenta una crítica de la metodología utilizada en investigaciones previas que intentaron evaluar los efectos sobre el bienestar social derivados de la existencia de empresas con poder de mercado en México.
Luis Alberto Ibarra
doaj  

New Firm entry and ESG performance: An inverted-U curve from spillovers to involution

International Review of Economics & Finance
Against the backdrop of China's growing emphasis on corporate ESG performance and the prevalence of involutional competition within industries, this study examines the impact of new firm entry on the ESG performance of incumbent firms, using panel data ...
Conghao Zhu, Tingting Wang
doaj   +1 more source

Bakteri ribosoomide uurimus keemilise modifitseerimise meetoditega [PDF]

, 2010
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Ribosoom on suur makromolekulaarne kompleks, mis kodeerib päriliku informatsiooni valgulisse olemusse.
Pulk, Arto
core  

Characterization of the binding sites of protein L11 and the L10.(L12)4 pentameric complex in the GTPase domain of 23 S ribosomal RNA from Escherichia coli

, 1990
Udgivelsesdato: 1990-May-20Ribonuclease and chemical probes were used to investigate the binding sites of ribosomal protein L11 and the pentameric complex L10.(L12)4 on Escherichia coli 23 S RNA.
Egebjerg, J, Egebjerg, Jan, Douthwaite, Stephen R., Garrett, Roger A., Garrett, R A, Liljas, A, Douthwaite, S R, Liljas, Anders   +7 more
core   +1 more source

Optimum level of lipid in granulated microdiets for largemouth bass (Micropterus salmoides) larvae

Animal Advances
This experiment was conducted to investigate the optimum lipid requirement for largemouth bass larvae. A total of 2,000 larval largemouth bass (0.06 ± 0.01 g) were randomly divided into five groups with four replicates per group.
Yuwan Li, Yutong Xie, Haohui Liang, Xiaoying Chen, Junru Hu, Xifeng Zhu, Guoxia Wang   +6 more
doaj   +1 more source