A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
Advanced Science, EarlyView.SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source
Enhancing cross-modal retrieval via label graph optimization and hybrid loss functions. [PDF]
Sci RepWang L, Wang C, Peng S.
europepmc +1 more source
Ultrastrong TEMPO‐Oxidized Densified Bamboo via Interface Decoupling and Hierarchical Toughening
Advanced Science, EarlyView.This study develops TEMPO‐oxidized densified bamboo that achieves ultrahigh strength and toughness by decoupling rigid hydrogen bonds into reversible van der Waals interactions. TEMPO oxidation reorganizes the cellulose hydrogen‐bonding network, facilitating energy dissipation via reversible interactions, thereby establishing a general strategy to ...
Ziyu Ba +5 more
wiley +1 more source
Inactive but Essential: The Role of the Inactive State of E49 in the Mechanism of the Alpha Subunit of Tryptophan Synthase and Its Stand-Alone Blueprint <i>Zm</i>BX1. [PDF]
ACS CatalDuran C, Osuna S.
europepmc +1 more source
Ni Single‐Atom Modulation of Ti‐O Covalency Boosts Ammonia Oxidation Electrocatalysis
Advanced Science, EarlyView.A Ni single‐atom‐induced enhancement of Ti‐O covalency in Ni SAC@TiO2 generates abundant active sites and promotes selective NHx‐NHy mediated N2 evolution while suppressing poisonous NOx formation, achieving nearly doubled AOR activity with excellent durability.
Subhash Chandra Shit +7 more
wiley +1 more source
The Concurrent and Longitudinal Contributions of Linguistic and Cognitive Skills to L2 Writing Quality. [PDF]
J IntellZhao A, Chen F, Li X.
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Advanced Science, EarlyView.Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Quantitative MRI assessment of paraspinal muscles and the psoas: associations with low back pain. [PDF]
Quant Imaging Med SurgOzenbas C, Ozturk CA, Altinok T.
europepmc +1 more source
Deformation‐Induced Formation of Stray Grains in Additive Manufacturing of Single Crystals
Advanced Science, EarlyView.Stray grain formation severely limits the additive manufacturing of single‐crystal alloys. By integrating in situ synchrotron techniques, ex situ characterization, and multi‐scale multi‐physics modeling, the authors reveal that stray grains originate from dislocations at the solid‐liquid interface, rather than thermal supercooling in conventional ...
Dongsheng Zhang +11 more
wiley +1 more source