Results 161 to 170 of about 331,175 (298)

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Dielectric‐Confinement‐Induced in‐Plane Photoelectric Anisotropy in Isotropic Quasi‐1D γ‐GaS Nanoribbon

Advanced Science, EarlyView.
We investigate the geometry‐governed optoelectronic anisotropy arising from dielectric confinement in quasi‐1D γ‐GaS nanoribbons with intrinsically isotropic atomic structures. Dielectric mismatch between the nanoribbon and its surroundings leads to a general polarization‐dependent photoresponse during near‐field scattering.
Jiawei Jing, Jiamei Chen, Xing Xin, Peisong Peng, Zhihao Wu, Weiheng Zhong, Hanyu Zhang, Wanfu Shen, Jihua Zhang, Yuwei Shan, Yuanzheng Li, Xingang Zhao, Wei Xin, Fang Wang, Weida Hu, Haiyang Xu, Yichun Liu   +16 more
wiley   +1 more source

Tailoring Multifunctional Carbon Dots via Precursor Stoichiometry: Switching Between Solid‐State Fluorescence and Broadband Absorption Through Aggregation Control

Advanced Science, EarlyView.
Precursor stoichiometry programs the surface chemistry of carbon dots, directing their self‐assembly into distinct aggregation modes. Aldehyde‐enriched surfaces form ordered, hydrogen‐bonded assemblies that enable bright red solid‐state fluorescence, whereas amine‐rich surfaces promote compact π–π stacked aggregates with broadband visible‐light ...
Gaixia Yang, Hao Sun, Defa Hou, Fulin Yang, Yuan Zou, Bei Zhou, Lanxiang Liu, Xu Lin, Guanben Du   +8 more
wiley   +1 more source

Atroposelective Access to π‐Conjugated 1,2‐Azaborepines Enabled by Palladium‐Catalyzed Cyclization of N‐Heterobiaryls with Alkynylboronates

Advanced Science, EarlyView.
We report a palladium‐catalyzed atroposelective cyclization of N‐heterobiaryl triflates with alkynyl boronates to access seven‐membered 1,2‐BN‐bridged biaryls with high yields and excellent enantioselectivity via a cascade DyKAT, cis‐carbopalladation, and 1,2‐migration, which expands the toolbox for axially chiral π‐conjugated boron compounds and opens
Fengya He, Zhen Wang, Haoyu Guo, Shuguang Chen, Xu Zhang, Yongjia Shang, Hui Wang   +6 more
wiley   +1 more source

Motivation, Language Identity and the L2 Self

With contributions by leading European, North American and Asian scholars, this volume offers a comprehensive anthology of conceptual and empirical papers describing the latest developments in L2 motivation research that involves the reframing of ...
Dörnyei, Zoltán., Ushioda, Ema.
core  

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

TRIM: Simultaneous Thermometry, Ranging, and Imaging via a Monolithic Metalens

Advanced Science, EarlyView.
ABSTRACT While metasurfaces offer a pathway beyond the discrete architectures of conventional LWIR systems, physically fusing high‐precision thermometry and passive ranging onto a single metalens remains a formidable challenge. Here, we demonstrate a monolithic, dual‐focus metalens capable of simultaneous multidimensional sensing.
Man Yuan, Yuqing Zhang, Wangzhe Zhou, Zhaojian Zhang, Xiaoyun He, Xinpeng Jiang, Yiyi Li, Xin He, Jiagui Wu, Yuanmu Yang, Junbo Yang   +10 more
wiley   +1 more source

Imaging Electric Polarization Switching in Multilayer Graphene

Advanced Science, EarlyView.
Domain wall sliding‐induced electric polarization switching is directly observed for the first time in multilayer graphene, enabled by a novel optical readout method. The polarization switching is realized upon application of global and local electric fields, and mechanical forces between neighboring polar domains of opposite out‐of‐plane polarizations
Zhou Zhou, Xiyao Peng, Jianfeng Bi, Jing He, Fei Xue, Jie Jiang, Huizhen Wu, Zhiwen Shi, Haoliang Qian, Toshikaze Kariyado, Sihan Zhao   +10 more
wiley   +1 more source

Hindsight is 20/20, an unexpected ocular telltale sign of bilateral renal artery dissection

American Journal of Ophthalmology Case Reports, 2023
Liyung T. Chou, Azin Abazari
doaj   +1 more source

Dichotomous keys for morphological identification of spores produced by arbuscular mycorrhizal fungi (phylum Glomeromycota) integrating the mode of spore formation and a spore developmental model. [PDF]

Mycorrhiza
Stürmer SL, Kemmelmeier K, Lubin TK, Koziol L, Schultz PA, Bever JD, Morton JB.   +6 more
europepmc   +1 more source