Results 191 to 200 of about 396,211 (234)

Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36. [PDF]

open access: yesJ Virol
Alvarez J   +11 more
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

open access: yesAdvanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang   +10 more
wiley   +1 more source

Sublattice‐Resolved Magnetoelastic Coupling and Opposing Pressure Responses in the Frustrated Magnetocaloric GdMn2O5

open access: yesAdvanced Science, EarlyView.
In GdMn2O5, sublattice‐resolved EXAFS and diffraction analysis reveal pronounced spin‐phonon coupling and an unexpected opposing pressure response: the Mn‐driven Néel temperature slightly decreases while the Gd‐sublattice ordering temperature rises under pressures up to 0.86 GPa.
Romualdo S. Silva Jr.   +9 more
wiley   +1 more source

AI‐Powered, Temperature‐Resolved Centrifugal Microfluidics for Rapid 3D Phase‐Diagram Generation of Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li   +6 more
wiley   +1 more source

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