Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression
T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera +5 more
wiley +1 more source
Ultrasonication-driven optimization of cricket protein nanoemulsions: influence of pH and rheological stabilizers. [PDF]
Sánchez-García RM +3 more
europepmc +1 more source
The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna +4 more
wiley +1 more source
Coelectrolysis of PET and CO<sub>2</sub> Using an Electrochemically Restructured Co-MOF-74 Anode and a Polymeric Co-Phthalocyanine Cathode. [PDF]
Rojas-Luna R +9 more
europepmc +1 more source
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source
Exploring anatomical and geographical drivers of the microbiota in wild capybaras (Hydrochoerus hydrochaeris): Baseline Data for zoonotic risk assessment. [PDF]
Camargo M +10 more
europepmc +1 more source
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source
Vasculogenic potential of adipose tissue derived stem cells from patients with chronic spinal cord injury and pressure injuries. [PDF]
Santos-De-La-Mata Á +12 more
europepmc +1 more source
Fiscal Opacity and Lack of Consensus in Expectations for External Sector Variables
ABSTRACT Fiscal transparency is essential for the expectations formation process, as governmental fiscal opacity often leads to forecast errors due to insufficient information. This study examines the relationship between fiscal unpredictability, particularly related to the primary budget, and the lack of consensus in expectations for external sector ...
Gabriel Caldas Montes +2 more
wiley +1 more source
Layer-by-layer decoding of contemporary and historic painting composition using MALDI mass spectrometry imaging and machine learning. [PDF]
Krupička V +7 more
europepmc +1 more source

