Results 31 to 40 of about 26,526 (256)

Evolvable Smartphone-Based Platforms for Point-of-Care In-Vitro Diagnostics Applications

Diagnostics, 2016
The association of smart mobile devices and lab-on-chip technologies offers unprecedented opportunities for the emergence of direct-to-consumer in vitro medical diagnostics applications.
François Patou, Fatima AlZahra’a Alatraktchi, Claus Kjægaard, Maria Dimaki, Jan Madsen, Winnie E. Svendsen   +5 more
doaj   +1 more source

Lab-on-Chip Culturing System for Fungi—Towards Nanosatellite Missions

Applied Sciences, 2022
In this paper, a lab-on-chip system dedicated to fungi cultivation in Earth’s gravity and simulated microgravity, being a solution that could be used in future nanosatellite missions, is shown.
Agnieszka Krakos (Podwin), Patrycja Śniadek, Marta Jurga, Marcin Białas, Agata Kaczmarek-Pieńczewska, Krzysztof Matkowski, Rafał Walczak, Jan Dziuban   +7 more
doaj   +1 more source

Development of a microfluidic system with a bearing micropump for applying fluid shear force in an intervertebral disc degeneration model involving mechanical stimulation [PDF]

Organoid
Background The intervertebral disc (IVD) functions as a shock absorber with viscoelastic tissues, including the gelatinous nucleus pulposus and the collagenous annulus fibrosus (AF).
Jae-Won Lee, Seoung Min Back, Tae-Won Kim, Hyuk Choi   +3 more
doaj   +1 more source

Portable microfluidic devices for in-field detection of pharmaceutical residues in water: Recent outcomes and current technological situation – A short review

Case Studies in Chemical and Environmental Engineering, 2021
The presence of pharmaceutical residues in urban and non-urban water is a reflection of the continuous growth of an essential industry, whose residues are often released into the environment throughout the manufacturing processes of commercial drugs, and
Mario E. Barocio, Enrique Hidalgo-Vázquez, Yuna Kim, Laura Isabel Rodas-Zuluaga, Wei-Ning Chen, Damià Barceló, Hafiz N.M. Iqbal, Roberto Parra-Saldívar, Carlos Castillo-Zacarías   +8 more
doaj   +1 more source

Microfluidic technologies: from fundamental principles to advanced fabrication and applications

AAPS Open
Conventional drug delivery systems, model study systems, drug analysis systems and drug interactions systems have been in use since ages. But these conventional methods struggle with significant limitations like lack of precise targeting, irregular ...
Rupam Deka, Shrutie Shivam, Debarupa Dutta Chakraborty, Prithviraj Chakraborty   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review

Micromachines, 2018
One of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM.
Daniela Pranzo, Piero Larizza, Daniel Filippini, Gianluca Percoco   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Rational Design of a Planar Junctionless Field-Effect Transistor for Sensing Biomolecular Interactions

Proceedings
In the ElectroMed project, we are interested in screening certain peptide sequences for their ability to selectively interact with antibodies or MHC proteins.
Rajendra P. Shukla, Johan G. Bomer, Daniel Wijnperle, Naveen Kumar, Janwa El Maiss, Divya Balakrishanan, Aruna Chandra Singh, Vihar P. Georgiev, Cesar Pascual Garcia, Sivashankar Krishnamoorthy, Sergii Pud   +10 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source