Results 31 to 40 of about 127,029,388 (136)

Microneedles in Advanced Microfluidic Systems: A Systematic Review throughout Lab and Organ-on-a-Chip Applications

Pharmaceutics, 2023
Microneedles (MNs) have been widely used in biomedical applications for drug delivery and biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to be combined with microfluidic devices. For that purpose, lab- or organ-on-a-
Renata Maia, Violeta Carvalho, Rui Lima, Graça Minas, Raquel O. Rodrigues   +4 more
doaj   +1 more source

Recent Progress in Lab-On-a-Chip Systems for the Monitoring of Metabolites for Mammalian and Microbial Cell Research

Sensors, 2019
Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites.
Esma Dervisevic, Kellie L. Tuck, Nicolas H. Voelcker, Victor J. Cadarso   +3 more
doaj   +1 more source

Lab on a chip for continuous-flow magnetic cell separation [PDF]

, 2015
Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the various methods, magnetic separation of cells utilizing microfluidic devices offers the merits of biocompatibility, efficiency, and simplicity.
Nguyen, Nam-Trung, Hejazian, Majid, Weihua Li, Li, Weihua, Nam-Trung Nguyen, Nam-Trung, Nguyen, Majid Hejazian   +6 more
core   +1 more source

Rapid determination of vitamin B12 concentration with a chemiluminescence lab on a chip [PDF]

, 2012
This paper reports a novel method for the rapid determination of vitamin B12 concentration in a continuous-flow lab-on-a-chip system. This new method is based on luminol-peroxide chemiluminescence (CL) assays for the detection of cobalt(II) ions in ...
Nguyen, Nam-Trung, binte Abdul Muttalib, Siti Zubaidah, Muttalib, Siti Zubaidah Binte Abdul, Kwok, Yien Chian, Foo Lee, Peter Peng, Siti Zubaidah Abdul Muttalib, Lok, Khoi Seng, Lee, Peter Peng Foo   +7 more
core   +1 more source

High-resolution and multi-range particle separation by microscopic vibration in an optofluidic chip

, 2017
An optofluidic chip is demonstrated in experiments for high-resolution and multi-range particle separation through the optically-induced microscopic vibration effect, where nanoparticles are trapped in loosely overdamped optical potential wells created ...
Zhang, Jing Bo, Liedberg, B., Liedberg, Bo, P. H. Yap, Y. Zhang, Yap, P. H., Zhang, Yi, Xiong, S., Zhang, Y., Chen, T. N., Y. L. Hao, Chin, Lip Ket, Chin, L. K., S. Xiong, Shi, Yu Zhi, Ser, Wee, Y. Yang, W. Ser, Liu, A. Q., J. B. Zhang, Xiong, Sha, Hao, Yi Long, J. H. Wu, Hao, Y. L., Chen, Tian Ning, A. Q. Liu, Y. Z. Shi, Wu, Jiu Hui, Zhang, J. B., B. Liedberg, Yang, Z. C., Yang, Y., Wu, J. H., Ser, W., Yang, Zhen Chuan, Yap, Peng Huat, Shi, Y. Z., Liu, Ai Qun, T. N. Chen, Z. C. Yang, L. K. Chin, Yang, Yi   +41 more
core   +1 more source

Highly-integrated lab-on-chip system for point-of-care multiparameter analysis

, 2022
S.464-473A novel innovative approach towards a marketable lab-on-chip system for point-of-care in vitro diagnostics is reported. In a consortium of seven Fraunhofer Institutes a lab-on-chip system called "Fraunhofer ivD-platform" has been established ...
Burgard, Matthias, Palzer, Silke, Grzesiak, Andrzej, Nebling, Eric, Albers, Jörg, Nestler, Jörg, Wegener, Michael, Brandenburg, Albrecht, Koger, Birgit, Ehrentreich-Förster, Eva, Sohn, Kai, Teichert, Andreas, Wunderlich, Kai, Weber, Achim, Michel, Dirk, Bier, Frank F., Schumacher, Soeren, Otto, Thomas   +17 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Fabricating electrodes for amperometric detection in hybrid paper/polymer lab-on-a-chip devices

, 2022
S.3281-3284We present a novel, low-resource fabrication and assembly method for creating disposable amperometric detectors in hybrid paper-polymer devices.
Ducrée, J., Godino, N., Gorkin, R., Bourke, K.   +3 more
core   +1 more source