Results 271 to 280 of about 104,822 (332)

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

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Lab-On-Chip Platforms for Environmental Analysis

2018
Environmental pollution is a crucial global concern. Many pollutants such as and pharmacetical compounds, heavy metals and industrial dye compounds in environmental samples display hazardous effects to humans, animals and plants. Therefore, the careful monitoring of these pollutants in environmental samples very important.
Büyüktiryaki S., Sümbelli Y., Keçili R., Hussain C.M.   +3 more
openaire   +4 more sources

Lab-on-Chip Devices: Gaining Ground Losing Size

ACS Nano, 2017
Portable analytical devices are notably gaining relevance in the panorama of urgent testing. Such devices have the potential to play an important role as easy-to-handle tools in critical situations. Epidemic infectious disease agents (e.g., Ebola virus, Coronavirus, Zika virus) could be controlled more easily by testing travelers on-site at the country
Veronica C. Romao, Sofia A. M. Martins, Jose Germano, Filipe A. Cardoso, Susana Cardoso, Paulo P. Freitas   +5 more
openaire   +3 more sources

Multifunctional System-on-Glass for Lab-on-Chip applications

Biosensors and Bioelectronics, 2017
Lab-on-Chip are miniaturized systems able to perform biomolecular analysis in shorter time and with lower reagent consumption than a standard laboratory. Their miniaturization interferes with the multiple functions that the biochemical procedures require.
PETRUCCI, GIULIA, CAPUTO, Domenico, LOVECCHIO, NICOLA, COSTANTINI, FRANCESCA, LEGNINI, IVANO, BOZZONI, Irene, NASCETTI, Augusto, DE CESARE, Giampiero   +7 more
openaire   +4 more sources

Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform

IEEE Transactions on Biomedical Circuits and Systems, 2021
ESR1 mutations are important biomarkers in metastatic breast cancer. Specifically, p.E380Q and p.Y537S mutations arise in response to hormonal therapies given to patients with hormone receptor positive (HR+) breast cancer (BC).
G. Alexandrou, Nicolas Moser, Katerina-Theresa Mantikas, J. Rodriguez-Manzano, Simak Ali, R. C. Coombes, J. Shaw, P. Georgiou, Christofer Toumazou, M. Kalofonou   +9 more
semanticscholar   +1 more source

Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors.

Lab on a Chip, 2021
Determining the nitrate levels is critical for water quality monitoring, and traditional methods are limited by high toxicity and low detection efficiency.
F. Wang, Jiaomeng Zhu, Xuejia Hu, Longfei Chen, Y. Zuo, Yi Yang, F. Jiang, Chengjun Sun, Wei-hong Zhao, Xiaotian Han   +9 more
semanticscholar   +1 more source

Microfluidics: Recent Advances Toward Lab‐on‐Chip Applications in Bioanalysis

Advanced Engineering Materials, 2021
Microfluidics is an emerging technology of flow and control of fluids in microscale volume that offers highly specialized solutions to rapid, sensitive, noninvasive analysis and measurements in various engineering applications.
Bharat Sharma, Ashutosh Sharma
semanticscholar   +1 more source