Results 41 to 50 of about 67,874,633 (306)

LAB ON CHIP: USEFULNESS, ADVANTAGES AND APPLICATIONS

open access: yes, 2022
reservedL’età media della popolazione mondiale cresce sempre di più ogni anno, mettendo in evidenza un ritmo che non conosce precedenti; inoltre, oltre all’innalzamento dell’aspettativa di vita, si è verificata una transizione epidemiologica nella ...
MATTIELLO, NOEMI
core  

Brain inspired iontronic fluidic memristive and memcapacitive device for self-powered electronics

open access: yesMicrosystems & Nanoengineering
Ionic fluidic devices are gaining interest due to their role in enabling self-powered neuromorphic computing systems. In this study, we present an approach that integrates an iontronic fluidic memristive (IFM) device with low input impedance and a ...
Muhammad Umair Khan   +4 more
doaj   +1 more source

Microfluidic Construction of Hierarchically Composite Superballs for Sensing Applications

open access: yesProceedings, 2018
Colloidal photonic crystals have attracted much attention of the scientific world due to their unique optical properties and potential applications in sensing, displays, optoelectronics, controlled superwetting and other fields.
Juan Wang   +3 more
doaj   +1 more source

Alginate Bead Biosystem for the Determination of Lactate in Sweat Using Image Analysis

open access: yesBiosensors, 2021
Lactate is present in sweat at high concentrations, being a metabolite of high interest in sport science and medicine. Therefore, the potential to determine lactate concentrations in physiological fluids, at the point of need with minimal invasiveness ...
Sandra Garcia-Rey   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Oncoimmunology Meets Organs-on-Chip

open access: yesFrontiers in Molecular Biosciences, 2021
Oncoimmunology represents a biomedical research discipline coined to study the roles of immune system in cancer progression with the aim of discovering novel strategies to arm it against the malignancy.
Fabrizio Mattei   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Ultrasound assisted particle and cell manipulation on-chip [PDF]

open access: yes, 2013
Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ...
Cochran, Sandy   +2 more
core   +1 more source

Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery

open access: yesScientific Reports, 2017
We demonstrate an in vitro microfluidic cell culture platform that consists of periodic 3D hydrogel compartments with controllable shapes. The microchip is composed of approximately 500 discontinuous collagen gel compartments locally patterned in between
Burcu Gumuscu   +4 more
doaj   +1 more source

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