Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging. [PDF]
Min J +11 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Label-free quantification of early virus-induced cellular responses by digital holographic tomography. [PDF]
Kublicka A +9 more
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
A label-free impedimetric strategy using interdigitated electrodes for tetracycline detection in Milk. [PDF]
Nguyen SH, Nguyen HQ, Tran MT.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
From Spectral Maps to Biomedical Evidence: A Minimum Evidentiary Framework for Label-Free Raman Imaging (Reply to Letter-to-the-Editor). [PDF]
Li J, Zhao X, Yu J.
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Label-Free Profiling of Immunoglobulin Isotypes Using Solid-State Nanopores. [PDF]
Ansah IB, Freedman KJ.
europepmc +1 more source

