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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Label Distribution Learning with Label Correlations on Local Samples

IEEE Transactions on Knowledge and Data Engineering, 2021
Label distribution learning (LDL) is proposed for solving the label ambiguity problem in recent years, which can be seen as an extension of multi-label learning. To improve the performance of label distribution learning, some existing algorithms exploit label correlations in a global manner that assumes the label correlations are shared by all ...
Weiwei Li, Zechao Li, Sheng-Jun Huang
exaly   +2 more sources

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