Results 61 to 70 of about 695,542 (311)

Optimization Of Detergent-Mediated Reconstitution Of Influenza A M2 Protein Into Proteoliposomes [PDF]

, 2018
We report the optimization of detergent-mediated reconstitution of an integral membrane-bound protein, full-length influenza M2 protein, by direct insertion into detergent-saturated liposomes.
Arbuckle, Douglas Stuart, , \u2717, Bost, Margaret H., , \u2717, Crouch, Catherine Hirshfeld, Green, Bryan M., , \u2716, Grossman, Carl H., Howard, Kathleen P., Kim, Tae H., , \u2714   +6 more
core   +2 more sources

Traffic Engineering with Segment Routing: SDN-based Architectural Design and Open Source Implementation

, 2015
Traffic Engineering (TE) in IP carrier networks is one of the functions that can benefit from the Software Defined Networking paradigm. By logically centralizing the control of the network, it is possible to "program" per-flow routing based on TE goals ...
Davoli, Luca, Salsano, Stefano, Siracusano, Giuseppe, Veltri, Luca, Ventre, Pier Luigi   +4 more
core   +1 more source

Performance evaluation of MPLS-enabled communications infrastructure for wide area monitoring systems [PDF]

, 2015
In order to obtain the transient power system measurement information, Wide Area Monitoring Systems (WAMS) should be able to collect Phasor Measurement Unit (PMU) data in a timely manner.
Ashton, PM, Golshani, M, Pisica, I, Taylor, GA   +3 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

A Quantum solution to the Byzantine agreement problem [PDF]

, 2001
We present a solution to an old and timely problem in distributed computing. Like Quantum Key Distribution (QKD), quantum channels make it possible to achieve taks classically impossible.
A. Ekert, A. Karlsson, C. Bennett, E. F. Galvão, L. Lamport, M. Fitzi, M. Hillery, M. J. Fischer, Matthias Fitzi, Nicolas Gisin, P. W. Shor, R. Cleve, Ueli Maurer, W. Tittel   +13 more
core   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Flow Cytometry Analysis of Microglial Phenotypes in the Murine Brain During Aging and Disease

Bio-Protocol
Microglia, the brain's primary resident immune cell, exists in various phenotypic states depending on intrinsic and extrinsic signaling. Distinguishing between these phenotypes can offer valuable biological insights into neurodevelopmental and ...
Jillian Cox, Kevin Pham, Alex Keck, Zsabre Wright, Manu Thomas, Willard Freeman, Sarah Ocañas   +6 more
doaj   +1 more source

PUREAIR protocol: randomized controlled trial of intensive pulmonary rehabilitation versus standard care in patients undergoing surgical resection for lung cancer

BMC Cancer, 2017
Background Non-small cell lung cancer is the most common type of lung cancer. Surgery is proven to be the most effective treatment in early stages, despite its potential impact on quality of life. Pulmonary rehabilitation, either before or after surgery,
Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Besa Kopliku, Cristian Rapicetta, Roberto Piro, Roberta Bardelli, Patricia Filipa Sobral Rebelo, Carla Galeone, Giorgio Sgarbi, Filippo Lococo, Massimiliano Paci, Tommaso Ricchetti, Silvio Cavuto, Domenico Franco Merlo, Sara Tenconi   +15 more
doaj   +1 more source

Supervised learning with quantum enhanced feature spaces

, 2018
Machine learning and quantum computing are two technologies each with the potential for altering how computation is performed to address previously untenable problems.
Chow, Jerry M., Córcoles, Antonio D., Gambetta, Jay M., Harrow, Aram W., Havlicek, Vojtech, Kandala, Abhinav, Temme, Kristan   +6 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source