Results 61 to 70 of about 666,217 (308)

PUREAIR protocol: randomized controlled trial of intensive pulmonary rehabilitation versus standard care in patients undergoing surgical resection for lung cancer

BMC Cancer, 2017
Background Non-small cell lung cancer is the most common type of lung cancer. Surgery is proven to be the most effective treatment in early stages, despite its potential impact on quality of life. Pulmonary rehabilitation, either before or after surgery,
Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Besa Kopliku, Cristian Rapicetta, Roberto Piro, Roberta Bardelli, Patricia Filipa Sobral Rebelo, Carla Galeone, Giorgio Sgarbi, Filippo Lococo, Massimiliano Paci, Tommaso Ricchetti, Silvio Cavuto, Domenico Franco Merlo, Sara Tenconi   +15 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Flow Cytometry Analysis of Microglial Phenotypes in the Murine Brain During Aging and Disease

Bio-Protocol
Microglia, the brain's primary resident immune cell, exists in various phenotypic states depending on intrinsic and extrinsic signaling. Distinguishing between these phenotypes can offer valuable biological insights into neurodevelopmental and ...
Jillian Cox, Kevin Pham, Alex Keck, Zsabre Wright, Manu Thomas, Willard Freeman, Sarah Ocañas   +6 more
doaj   +1 more source

Structured diabetes education program for improving self-care behavior in primary care settings of Puducherry: Evidence from a randomized controlled trial

Indian Journal of Community Medicine, 2019
Context: Diabetes self-management education plays a critical role in improving patients' clinical outcome and quality of life. Aims: This study aims to study the effectiveness of a structured diabetes educational program on improvement of self-care ...
Mamta Gehlawat, Subitha Lakshminarayanan, Sitanshu Sekhar Kar   +2 more
doaj   +1 more source

Information Gathering in Ad-Hoc Radio Networks with Tree Topology

, 2014
We study the problem of information gathering in ad-hoc radio networks without collision detection, focussing on the case when the network forms a tree, with edges directed towards the root.
A Alon, A Czumaj, A Strahler, AEF Clementi, BS Chlebus, BS Chlebus, D Bruschi, D Liu, DR Kowalski, DR Kowalski, E Kushilevitz, L Gasieniec, L Gąsieniec, M Chrobak, M Chrobak, M Talagrand, N Alon, P Erdös, P Erdös, R Bar-Yehuda, X Viennot, YX An   +21 more
core   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Optimization Of Detergent-Mediated Reconstitution Of Influenza A M2 Protein Into Proteoliposomes [PDF]

, 2018
We report the optimization of detergent-mediated reconstitution of an integral membrane-bound protein, full-length influenza M2 protein, by direct insertion into detergent-saturated liposomes.
Arbuckle, Douglas Stuart, , \u2717, Bost, Margaret H., , \u2717, Crouch, Catherine Hirshfeld, Green, Bryan M., , \u2716, Grossman, Carl H., Howard, Kathleen P., Kim, Tae H., , \u2714   +6 more
core   +2 more sources

Genebank ‐ in vitro propagation of potato and sweetpotato. CIP‐SOP056 V 3.0 [PDF]

, 2020
This procedure describes the in vitro multiplication of potato and sweetpotato germplasm for international and national germplasm distribution, as well as, in vitro conservation, phytosanitary, and cryopreservation ...
Anglin, N.L., Manrique, N., Panta, A., Solis, R., Vollmer, R.   +4 more
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Effect of a conventional energy-restricted modified diet with or without meal replacement on weight loss and cardiometabolic risk profile in overweight women

Nutrition & Metabolism, 2011
Background Abdominal obesity, atherogenic dyslipidemia and hypertension are essential risk factors for cardiovascular diseases. Several studies showed favorable effects of weight loss in overweight subjects on cardiometabolic risk profile.
Schäfer Sandy, Lemperle Martin, Bitterlich Norman, Folberth-Vögele Anke, Metzner Christine E, Alteheld Birgit, Stehle Peter, Siener Roswitha   +7 more
doaj   +1 more source