Results 141 to 150 of about 2,914,902 (352)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Sex differences in medication discontinuation in axial spondyloarthritis.

Arthritis Care &Research, Accepted Article.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or Janus kinase inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Optimized Time–Frequency Analysis for Induction Motor Fault Detection Using Hybrid Differential Evolution and Deep Learning Techniques

International Journal of Adaptive Control and Signal Processing, EarlyView.
Workflow of the parameter optimization process for ITSC fault detection, applying Differential Evolution optimization and the Smooth Pseudo Wigner‐Ville Distribution for signal processing. The optimized parameters are then used in the failure identification pipeline, which combines the signal processing with a YOLO‐based architecture for fault severity
Rafael Martini Silva, Avyner Lorran de Oliveira Vitor, Marcelo Favoretto Castoldi, Alessandro Goedtel, Wesley Angelino Souza   +4 more
wiley   +1 more source

Labeled Burst Switching

Journal of Applied Sciences, 2006
Hakim Mellah, Fouad Mohammed Abbou
openaire   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Flow-splitting algorithm of MPLS single label based on programmable router

Tongxin xuebao, 2014
To increase the QoS (quality of service) of data transmission, a novel flow-splitting algorithm, multipathMPLS, was proposed, which combined three technologies of MPLS (multi protocol label switching), concurrent multi-path and programmable router ...
Lai-quan HAN, Jin-kuan WANG, Xing-wei WANG   +2 more
doaj   +2 more sources

Semantically-Guided Image Compression for Enhanced Perceptual Quality at Extremely Low Bitrates

IEEE Access
Image compression methods based on machine learning have achieved high rate-distortion performance. However, the reconstructions they produce suffer from blurring at extremely low bitrates (below 0.1 bpp), resulting in low perceptual quality.
Shoma Iwai, Tomo Miyazaki, Shinichiro Omachi   +2 more
doaj   +1 more source

Analisa QoS pada Jaringan MPLS IPv6 Berbasis Routing OSPF [PDF]

Multi Protocol Label Switching (MPLS) architecture (network) is defined by IETF to incorporate label swapping mechanism in layer two and layer three routing that have beneficial to delivery of explicit routing package and provides all the advantages of ...
Rahmawati, Imas Dwi, Saleh, Akuwan, Winarno, Idris   +2 more
core  

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source