Results 201 to 210 of about 2,965,444 (278)

Development of a platform for quantum-dot-labeled polyethylene nanoplastics for dynamic analytical applications. [PDF]

RSC Adv
Hokaku M, Haga Y, Tanaka K, Tsujino H, Asahara H, Higashisaka K, Tsutsumi Y.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

An Evaluation of the Mean Teacher Framework for Semi-Supervised Cataract Surgical Image Segmentation. [PDF]

Transl Vis Sci Technol
Faraji M, Yi D, Heiferman MJ, Rashidisabet H.   +3 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Fetal-restricted hematopoietic progenitors arise from hemogenic endothelium in vitelline and umbilical arteries. [PDF]

Nat Cardiovasc Res
Barone C, Quattrini G, Muratore A, Anselmi G, Park Y, Mehmood NT, Morganti E, Orsenigo R, Timóteo-Ferreira F, Cazzola A, Patelli A, Milanesi T, Nesti B, Soares-da-Silva F, Nicholls M, Zambelli G, Mauri M, Bombelli S, De Marco S, D'Aliberti D, Spinelli S, Bonalume V, Domingues A, Naghavi Alhosseini M, Sala G, Colonna A, D'Errico E, D'Orlando C, Bianchi C, Perego RA, Meneveri R, Cumano A, Brunelli S, De Bruijn MFTR, Ditadi A, Fantin A, Piazza R, Azzoni E.   +37 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Yield Prediction of Organic Reactions in Biased Data Sets via Positive-Unlabeled Learning. [PDF]

J Am Chem Soc
Boser F, Spies JC, Glorius F.
europepmc   +1 more source