Results 131 to 140 of about 728,673 (266)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Ex vivo comparison of ACU193 and lecanemab reveals binding differences in mouse brain. [PDF]

open access: yesAlzheimers Dement
Grenon MB   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Toward Reliable Lesion Labeling Standards for AI in Nuclear Medicine. [PDF]

open access: yesJ Nucl Med
Poelarends RJ   +5 more
europepmc   +1 more source

To Label or Not to Label, That Is the Question

open access: yes
Functional Somatic Disorders (FSD) encompass conditions such as fibromyalgia (FM), chronic fatigue syndrome (CFS), and irritable bowel syndrome (IBS), which present persistent physical symptoms without identifiable biomedical abnormalities. FSDs significantly impact patients’ quality of life (QoL) and healthcare utilization.
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Response: Commentary: No evidence for language syntax in songbird vocalizations

open access: yesFrontiers in Ecology and Evolution
Marinus A. C. Huybregts   +4 more
doaj   +1 more source

A new method for visualizing cerebrovascular vessels. [PDF]

open access: yesFront Mol Neurosci
Gu Q, Raymick J, Sarkar S, Kanungo J.
europepmc   +1 more source

Home - About - Disclaimer - Privacy