ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Correction to: Incremental 2D self-labelling for effective 3D medical volume segmentation with minimal annotations. [PDF]
Anderson M, Habib M, Steel DH, Obara B.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Transforming Growth Factor-β Drives Epithelial Mesenchymal Transition and Reduces Synthesis of Unelaborated O-GalNAc Glycans in Breast Cancer Cells. [PDF]
Cull J, Pink RC, Samuel P, Brooks SA.
europepmc +1 more source
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Post-secondary student adoption of mental health labels through their use of social media: a scoping review. [PDF]
Alexander ED +4 more
europepmc +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Vitabel: A Python Framework for Visualizing and Labelling High-Resolution Physiological Data for Critical Care Machine Learning. [PDF]
Orlob S +5 more
europepmc +1 more source
Barriers and facilitators to dietary change while aiming to reduce free sugar intakes: framework analysis based on intervention, time for change, and success at 12 weeks. [PDF]
Boxall LR +4 more
europepmc +1 more source
Immunolocalization of matrix polysaccharides during wood decay by white rot fungus: evidence for specific interaction between hemicellulose and lignin in the wood fibre cell wall of <i>Dalbergia sissoo</i> Roxb. [PDF]
Sivan P, Rajput KS, Rao KS.
europepmc +1 more source

