Results 81 to 90 of about 187,141 (267)

Towards Label Imbalance in Multi-label Classification with Many Labels

open access: yesCoRR, 2016
In multi-label classification, an instance may be associated with a set of labels simultaneously. Recently, the research on multi-label classification has largely shifted its focus to the other end of the spectrum where the number of labels is assumed to be extremely large.
Li Li, Houfeng Wang
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Non‐Specific Particle Formation During Extracellular Vesicle Labelling With the Lipophilic Membrane Dye PKH26

open access: yesJournal of Extracellular Vesicles
Current approaches for the fluorescent labelling of extracellular vesicles (EVs) have been reported to produce widely variable and controversial results, highlighting a significant need for validated, reproducible labelling methods to advance the field ...
Laurel A. Haines   +6 more
doaj   +1 more source

Pollen from genetically modified plants in honey – problems with quantification and proper labelling

open access: yesJournal of Apicultural Science, 2013
Maize can be a valuable source of pollen when plants attractive for bees are not available. Honeybees can forage from conventional maize as well as from genetically modified (GM ) maize.
Żmijewska Ewelina   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Editorial: Animal welfare labelling

open access: yesFrontiers in Animal Science, 2023
Mara Miele, Harry Blokhuis
doaj   +1 more source

Scientific Opinion on the energy conversion factor of d‐tagatose for labelling purposes

open access: yesEFSA Journal, 2016
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the energy conversion factor of d‐tagatose to be used for calculating the energy value of ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)   +20 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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