Results 61 to 70 of about 8,067 (167)
Labetalol was used to treat systemic hypertension (systolic blood pressure above 150 mmHg) in 11 patients with acute myocardial infarction; its haemodynamic effects and tolerance were studied.
Jacobs, Paul +3 more
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Labetalol Prevents Intestinal Dysfunction Induced by Traumatic Brain Injury.
Beta-adrenergic blockade has been hypothesized to have a protective effect on intestinal dysfunction and increased intestinal permeability associated with the epinephrine surge after traumatic brain injury (TBI).Wister rats were subjected to either a ...
Chenhui Xi +4 more
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Monotherapy with labetalol compared with propranolol. Differential effects by race
The antihypertensive effect of oral labetalol and propranolol were evaluated in 65 black and 75 white patients with mild to moderate hypertension (standing diastolic blood pressure (StDBP) of 90-115 mmHg) in a double-blind multicenter clinical trial ...
McMahon, F G +5 more
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Antiarrhythmic action of labetalol and its effect on adenine metabolism in the isolated rat heart
Labetalol, a combined alpha- and beta-adrenergic antagonist, was assessed for antiarrhythmic activity in the isolated perfused rat heart. Inclusion of 5.0 and 7.5 μmol/ liter labetalol in the perfusate reduced the fall in ventricular fibrillation ...
Edwards, Margot F. +2 more
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Labetalol, a new adrenergic receptor antagonist, has both a- and B-blocking properties. Intravenous labetalol (0,25 and 0,5 mg/kg), practolol (0,4 mg/kg) and saline (1 ml), injected prior to anaesthesia, were compared with respect to their effect on the ...
Maharaj, R. J. +4 more
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Lipid Emulsion Mitigates the Cardiotoxic Effects of Labetalol in Rat Cardiomyoblasts
Lipid emulsion has recently emerged as an effective agent for improving the cardiotoxicity of highly lipophilic drugs. However, its effect on cardiotoxicity induced by labetalol, a nonselective beta-blocker, remains unknown.
Kyeong-Eon Park +5 more
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PurposeThe present study compared the efficacy of two different doses of labetalol, for attenuation of hemodynamic response to laryngoscopy and intubation in hypertensive patients.Patients and methods75 hypertensive patients, aged 18–60years undergoing ...
Kumar, Rajender +5 more
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Effects of maternal labetalol on the newborn infant
Forty eight neonates, born to mothers suffering from pregnancy induced hypertension and receiving labetalol for control of blood pressure, were studied for the possible adverse effects of the drug. These were compared with eighty one neonates matched for
Paul, V. K. +3 more
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Stereoselective Analysis of Labetalol in Human Plasma by LC-MS/MS: Application to Pharmacokinetics
Labetalol is clinically available as a mixture of two racemates (four stereoisomers). The stereoisomer (R,R) has as main activity the beta(1)-antagonism and the stereoisomer (S,R) is highly selective for the alpha(1) adrenoceptor and is responsible for ...
BARALDI, Claudia De Oliveira +5 more
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