Results 161 to 170 of about 82,995 (291)

Whole Genome Sequencing in Prenatal Diagnostics: The Danish Approach to Guideline Formation and Implementation Within Public Healthcare

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To describe the implementation of whole genome sequencing (WGS) in prenatal diagnostics and outline the national guideline system facilitating this. Methods Clinical guidelines for WGS in prenatal diagnostics were developed and implemented by the Danish Fetal Medicine Society.
Ida Vogel   +17 more
wiley   +1 more source

Current Controversies in Prenatal Diagnosis—Conference Debate 2024: All Fetuses Undergoing Fetal Therapy Should Have Exome Sequencing

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT This manuscript summarises the debate held at the 2024 annual meeting of The International Society for Prenatal Diagnosis (ISPD). Experts discussed whether all fetuses undergoing fetal therapy should undergo exome sequencing. Arguments in favor included that, with increasing experience and better clinical availability, exome sequencing can ...
Teresa N. Sparks   +2 more
wiley   +1 more source

Opportunities, Challenges, and Lessons Learned From Partograph Utilization for Labor Monitoring in Sub-Saharan Africa: A Systematic Review. [PDF]

open access: yesCureus
Mugyenyi GR   +8 more
europepmc   +1 more source

Prenatal Diagnosis of Horseshoe Lung: A Report of Three Cases and Review of the Literature

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Horseshoe lung is a rare congenital malformation in which the lungs are fused by a parenchymal isthmus. The current literature is very limited regarding cases of prenatal diagnosis and their outcome. Method We retrospectively examined three cases of fetuses with horseshoe lung diagnosed antenatally in our center from 2015 to 2024 ...
Benjamin Birene   +6 more
wiley   +1 more source

Is It Feasible to Screen for Fetal De Novo or Paternally Inherited Pathogenic Single Nucleotide Variants in Maternal Plasma Cell‐Free DNA? A Systematic Literature Review

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Monogenic disorders (MDs), often associated with developmental delay, intellectual disability, hypotonia, or dysmorphic facial features, typically go undetected during pregnancy. These disorders are frequently caused by de novo single nucleotide variants (SNVs), which are not currently covered by routine non‐invasive prenatal testing
Kristína Valovičová   +4 more
wiley   +1 more source

Adrift in a Sea of Uncertainty: Navigating the Challenges of Pregnancy, Postpartum, and Motherhood for Field‐Going Oceanographers

open access: yes
Limnology and Oceanography Bulletin, EarlyView.
Elizabeth D. Hetherington   +2 more
wiley   +1 more source

Diurnal Effects on the Fraction of Fetal Cell‐Free DNA in Maternal Plasma

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective The discovery of fetal cell‐free DNA (cfDNA) has revolutionized prenatal diagnostics through non‐invasive prenatal testing (NIPT), which depends on accurately measuring the fetal fraction (FF) in maternal plasma. While FF is known to be influenced by maternal and fetal factors, the impact of intraday rhythms remains unclear.
Alexander Gamisch   +2 more
wiley   +1 more source

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