Results 151 to 160 of about 49,848 (260)

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

open access: yesAdvanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen   +11 more
wiley   +1 more source

Volumetric Additive Manufacturing of Dormant Catalytic Chemistries to Generate Silicone Micro‐ and Millifluidic Devices and Instant Molds

open access: yesAdvanced Science, EarlyView.
We describe use of a novel zero‐dose approach to tomographic volumetric additive manufacturing that has enabled us to print silicone micro‐ and millifluidic devices and instant molds within minutes. The silicones are polymerized using photoactivated dormant platinum photohydrosilylation catalysts that would traditionally be difficult to access in ...
Johanna A. Vandenbrande   +12 more
wiley   +1 more source

Misoprostol Versus Oxytocin for Labor Induction in Term Prelabor Rupture of Membranes: A Systematic Review of Their Efficacy and Safety. [PDF]

open access: yesCureus
Hassan Abdalla MS   +7 more
europepmc   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

open access: yesAdvanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng   +7 more
wiley   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Is there a role for oral misoprostol in labor induction for prelabor rupture of membranes at term? [PDF]

open access: yesBMC Pregnancy Childbirth
Katz AA   +4 more
europepmc   +1 more source

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