Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu +5 more
wiley +1 more source
Low-dose oral misoprostol vs. oxytocin in premature rupture of membranes at ≥ 36 weeks: a comparison of labor induction outcomes and postpartum hemorrhage risk. [PDF]
Yang Y, Yu Z, Shi H, Wang Y, Zhao Y.
europepmc +1 more source
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin +5 more
wiley +1 more source
Editorial Expression of Concern: Comparative study of titrated oral misoprostol solution and vaginal dinoprostone for labor induction at term pregnancy. [PDF]
Wang X, Yang A, Ma Q, Li X, Qin L, He T.
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu +6 more
wiley +1 more source
Effects of Yixin Da cervical double-lumen balloon dilatation combined with low-dose oxytocin on cervical maturation in term labor induction. [PDF]
Wei T, Gao J, Sun S.
europepmc +1 more source
Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics [PDF]
Bennett, PR +9 more
core +1 more source
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen +9 more
wiley +1 more source
Exploring the risks of postpartum infections: Insights from labor induction practices. [PDF]
Zhao M, Xu L.
europepmc +1 more source

