Results 31 to 40 of about 1,859,719 (295)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Risk Factors for Cesarean Delivery following Labor Induction in Multiparous Women

Journal of Pregnancy, 2013
Objective. To identify potential risk factors for cesarean delivery following labor induction in multiparous women at term. Methods. We conducted a retrospective case-control study. Cases were parous women in whom the induction of labor had resulted in a
Corine J. Verhoeven, Cedric T. van Uytrecht, Martina M. Porath, Ben Willem J. Mol   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A comparative study between modified Bishop score and transvaginal sonography to predict successful induction of labor

Journal of Family Medicine and Primary Care
Background Modified Bishop score (MBS) and cervical length determination by transvaginal sonography (TVS) are the two methods for predicting successful vaginal delivery based on pre-induction favourability of the cervix.
Archana Sinha, Minakshi Sinha, Sushant K. Sharma, Dipali Prasad, Neeru Goel, Manisha Kumari   +5 more
doaj   +1 more source

Is there an increased risk of cesarean section in obese women after induction of labor? A retrospective cohort study.

PLoS ONE, 2022
BackgroundObesity is increasing in Sweden and is also of huge global concern. Obesity increases the risk of complications during pregnancy and the need for the induction of labor.
Jenny Bjorklund, Eva Wiberg-Itzel, Tove Wallstrom   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Comparison of Two Methods in Labor Induction in Nulliparous Women with Unfavorable Cervix at Term: Oxytocin Alone Versus Dinoprostone Vaginal Slow-Release System (Propess®) + Oxytocin

Gynecology Obstetrics & Reproductive Medicine, 2010
OBJECTIVES: To investigate the efficacy of two labor induction protocols. STUDY DESIGN: In this retrospective study, pregnancy records of 50 nulliparous singletons at term with intact membranes and Bishop score ≤ 6, delivered vaginally with one of the ...
Tunç Canda, Namık Demir, Orçun Sezer
doaj  

Success of trial of labor in women with a history of previous cesarean section for failed labor induction or labor dystocia: a retrospective cohort study

BMC Pregnancy and Childbirth, 2019
Background The rates of cesarean section (CS) are increasing worldwide leading to an increased risk for maternal and neonatal complications in the subsequent pregnancy and labor.
Katariina Place, Heidi Kruit, Aydin Tekay, Seppo Heinonen, Leena Rahkonen   +4 more
doaj   +1 more source