Results 81 to 90 of about 282,859 (304)

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

open access: yesAdvanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li   +12 more
wiley   +1 more source

The U.S. financial sector's value added: trends now and then [PDF]

open access: yes
The U.S. financial growth between 1995 and 2006 certainly translated into record-high shareholder returns.
Adrian Peralta-Alva   +1 more
core  

Long-Term Unemployment Over Men\u27s Careers [PDF]

open access: yes, 2013
[Excerpt] Since the start of the recent recession, which began in December 2007, many unemployed Americans have entered the ranks of the long-term unemployed (those who are unemployed for 27 weeks or more).
Rothstein, Donna S
core   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

open access: yesAdvanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang   +16 more
wiley   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

open access: yesAdvanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim   +12 more
wiley   +1 more source

Maternal postpartum infection risk following induction of labor: A Danish national cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica
Introduction Induction of labor is a common procedure, and in Denmark, approximately one in four vaginal deliveries are induced. The association between induction and maternal postpartum infections such as endometritis, surgical site infection after ...
Sidsel Hogh‐Poulsen   +5 more
doaj   +1 more source

Framing the Issues: Economic Research on Employment Policy for People with Disabilities [PDF]

open access: yes, 1999
This paper is designed to serve as a vehicle to engage the broad policy community in a discussion about proposed research to be conducted at Cornell’s Rehabilitation Research and Training Center (RRTC) for Economic Research on Employment Policy for ...
Fishman, Michael E
core   +1 more source

Evaluation of the impact of the Mother and Infant Health Project in Ukraine [PDF]

open access: yes, 2009
This paper exploits a unique opportunity to evaluate the impact of the quality change in the labor and delivery services brought about by the Mother and Infant Health Project in Ukraine.
Nizalova, Olena, Vyshnya, Maria
core   +2 more sources

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

Current Experience with Obstetrical Events: Characteristics and the Effects of Nocturnal Periods

open access: yesClinical and Experimental Obstetrics & Gynecology
Background: The object is to analyze the influence of the nocturnal period and lunar phases on the frequency of obstetrical events in pregnant women. Methods: This was a retrospective, transversal observational study of 1409 births in a hospital from ...
Susana Blanco-López   +5 more
doaj   +1 more source

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