Results 131 to 140 of about 785,423 (325)

Laboratory-based surveillance in the molecular era: The typened model, a joint data-sharing platform for clinical and public health laboratories [PDF]

, 2013
Laboratory-based surveillance, one of the pillars of monitoring infectious disease trends, relies on data produced in clinical and/or public health laboratories. Currently, diagnostic laboratories worldwide submit strains or samples to a relatively small
Avoort, H.G.A.M. (Harrie) van der, Baas, D., Benschop, K. (Kimberley), Claas, E.C.J. (Eric), Koopmans D.V.M., M.P.G. (Marion), Kroneman, A. (Annelies), Maarseveen, N.M. (Noortje) van, Niesters, H.G.M. (Bert), Pas, S.D. (Suzan), Pelt, W. (Wilfred) van, Rahamat-Langendoen, J. (Janette), Rossen, J.W. (John), Schuurman, R. (Rob), Vennema, H. (Harry), Verhoef, L. (Linda), Wolthers, K.C. (Katja)   +15 more
core   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1985
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1236/thumbnail ...

core   +1 more source

Development and validation of computable Phenotype to Identify and Characterize Kidney Health in Adult Hospitalized Patients [PDF]

arXiv, 2019
Background: Acute kidney injury (AKI) is a common complication in hospitalized patients and a common cause for chronic kidney disease (CKD) and increased hospital cost and mortality. By timely detection of AKI and AKI progression, effective preventive or therapeutic measures could be offered.
arxiv  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1969
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1032/thumbnail ...

core   +1 more source

Bacillus Calmette-Guerin 's beneficial impact on glucose metabolism: Evidence for broad based applications

iScience, 2021
Summary: Bacillus Calmette-Guerin (BCG) vaccinations improve glycemic control in juvenile-onset Type I diabetes (T1D), an effect driven by restored sugar transport through aerobic glycolysis.
Gabriella F. Shpilsky, Hiroyuki Takahashi, Anna Aristarkhova, Michele Weil, Nathan Ng, Kacie J. Nelson, Amanda Lee, Hui Zheng, Willem M. Kühtreiber, Denise L. Faustman   +9 more
doaj  

Simulating the blood transfusion system in Kenya: Modelling methods and exploratory analyses [PDF]

arXiv
The process of collecting blood from donors and making it available for transfusion requires a complex series of operations involving multiple actors and resources at each step. Ensuring hospitals receive adequate and safe blood for transfusion is a common challenge across low- and middle-income countries, but is rarely addressed from a system level ...
arxiv  

Medical Diagnosis From Laboratory Tests by Combining Generative and Discriminative Learning [PDF]

arXiv, 2017
A primary goal of computational phenotype research is to conduct medical diagnosis. In hospital, physicians rely on massive clinical data to make diagnosis decisions, among which laboratory tests are one of the most important resources. However, the longitudinal and incomplete nature of laboratory test data casts a significant challenge on its ...
arxiv