Results 51 to 60 of about 804,492 (282)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Comparing the Laboratory module of Hospital Information System software in Hospitals of Isfahan University of Medical Sciences, based on the International standard ISO 9241-110

مدیریت اطلاعات سلامت, 2015
Introduction: Hospital information systems are one of the most important systems in improving the quality of health care. Because of the enormous costs that would be spent for installation and implementation of health information systems, it is important
Mohammad Mahmoudi Maymand, Tahere Yaghoobi, Parnaz Naghdi sede   +2 more
doaj  

Tripronuclear Zygotes in IVF Laboratory Quality Control: Experimental Evaluation and Potential Applications

International Journal of General Medicine, 2022
Suzhu Chen,* Pengyu Huang,* Yan Sun,* Shengrong Du, Yunhong Lin, Beihong Zheng, Dianliang Lin Reproductive Medicine Center, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, 350001, People’s ...
Chen S, Huang P, Sun Y, Du S, Lin Y, Zheng B, Lin D   +6 more
doaj  

Ranunculus ternatus Thunb extract attenuates renal fibrosis of diabetic nephropathy via inhibiting SMYD2

Pharmaceutical Biology, 2022
Context Ranunculus ternatus Thunb (Ranunculaceae), (RTT) is used clinically for the treatment of tuberculosis or as tumour adjuvant therapy, but its potential effect on diabetic nephropathy (DN) has not been studied.
Weiwei Xu, Rui Peng, Siyu Chen, Congcong Wu, Xiaoxiao Wang, Ting Yu, Jiuying Jian, Ni Zhang, Siyang Zuo, Min Chen, Bing Guo, Lirong Liu   +11 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Measuring Operational Efficiency of Highly Specialised Clinical Laboratories at a University Teaching Hospital– A DEA Approach

Online Journal of Health & Allied Sciences, 2020
Purpose: Evaluation of the efficiencies of clinical laboratories is a must for the laboratory and hospital managers. It facilitates an understanding of the current situation of the ongoing processes and allows for targeted measures.
Vidya Jha, Dinesh TA, Abhijath V, Prem Nair   +3 more
doaj  

Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke

Nature Communications, 2022
Damaged brains try to repair themselves by producing neurons in areas where neurogenesis does not normally occur. Here, the authors show that brain endothelial cells provide microvesicle-encased signals that convert parenchymal astrocytes into neural ...
Wenlu Li, Emiri T. Mandeville, Violeta Durán-Laforet, Norito Fukuda, Zhanyang Yu, Yi Zheng, Aaron Held, Ji-Hyun Park, Takafumi Nakano, Masayoshi Tanaka, Jingfei Shi, Elga Esposito, Wanting Niu, Changhong Xing, Kazuhide Hayakawa, Ignacio Lizasoain, Klaus van Leyen, Xunming Ji, Brian J. Wainger, Maria A. Moro, Eng H. Lo   +20 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Situation Analysis of the Capacity of Laboratories in Faith-Based Hospitals in Zambia to Conduct Surveillance of Antimicrobial Resistance: Opportunities to Improve Diagnostic Stewardship

Microorganisms
Antimicrobial resistance (AMR) is a public health problem exacerbated by the overuse and misuse of antibiotics and the inadequate capacity of laboratories to conduct AMR surveillance.
Doreen Mainza Shempela, Steward Mudenda, Maisa Kasanga, Victor Daka, Mundia Hendrix Kangongwe, Mapeesho Kamayani, Jay Sikalima, Baron Yankonde, Cynthia Banda Kasonde, Ruth Nakazwe, Andrew Mwandila, Fatim Cham, Michael Njuguna, Bertha Simwaka, Linden Morrison, Joseph Yamweka Chizimu, John Bwalya Muma, Roma Chilengi, Karen Sichinga   +18 more
doaj   +1 more source

The future of laboratory medicine - A 2014 perspective. [PDF]

, 2015
Predicting the future is a difficult task. Not surprisingly, there are many examples and assumptions that have proved to be wrong. This review surveys the many predictions, beginning in 1887, about the future of laboratory medicine and its sub ...
FORTINA, PAOLO, Kricka LJ, Park JY, Polsky TG   +3 more
core   +1 more source