Results 51 to 60 of about 503,272 (261)
Laboratory Diagnosis of Nosocomial Bacterial Infections Using Standard Methods
Medical Laboratory Journal, 2016 Background and objective: Implementation of standard methods for accurate detection of bacteria, correct antibiotic susceptibility testing and effective treatment of bacterial infections play important roles in development of public health and prevention
Saeideh Sadat Shobeiri +4 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Lean Methodology for Pathology Laboratories: A Case Study from a Public Hospital
Türk Patoloji Dergisi, 2019 Objective: The increase in the financial imposition of laboratories together with developing technology and evidence-based medicine applications increased the importance of quality and efficiency studies in laboratories.
Fatih DURUR, Yasemin AKBULUT
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Mediators of Inflammation, 2016 The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a challenge ...
Lang Yi +15 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Evaluation of Antibiotic Susceptibility of Enterobacteriacea Isolates from Blood Cultures [PDF]
پیاورد سلامت, 2007 Background: Septicemia is a life threatening status and needs rapid antibiotic treatment. Enterobacteriacea are one of the most important causes of septicemia.
Y Erfani +6 more
doaj +1 more source
Payesh, 2017 Objective (s): Equity in distribution of health services is one of the goals of health policy makers. Thus, an study entitled “modeling geographical access to medical laboratory services in Iran” was conducted in 2014. The present article is a case study
Jila Sadighi +10 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Indagine nazionale sulle metodiche per emocoltura in Italia
Microbiologia Medica, 2004 Sepsis is an important cause of morbidity and mortality; Blood cultures are the standard for identifying the responsible pathogen, bacteria or fungi.A number of factors influence the yield of blood culture, most of them concerning the microbiolist skill ...
Antonio Goglio, Pierluigi Nicoletti
doaj +1 more source