Results 81 to 90 of about 799,236 (303)

The relationship between measurement uncertainty and reporting interval [PDF]

, 2014
Background Measurement uncertainty (MU) estimates can be used by clinicians in result interpretation for diagnosis and monitoring and by laboratories in assessing assay fitness for use and analytical troubleshooting.
Badrick, Tony, Hawkins, Robert C.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1975
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1113/thumbnail ...

core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Laboratory diagnostics performance in Uganda: A survey of test availability and constraints

Journal of Interventional Epidemiology and Public Health
Introduction: Clinical laboratory services are a critical component of the health system for effective disease diagnosis, treatment, control and prevention. However, many laboratories in Sub-Saharan Africa remain dysfunctional.
Noel Namuhani, Suzanne Namusoke Kiwanuka, Martha Akulume, Simeon Kalyesubula, William Bazeyo, Angela Nakanwagi Kisakye   +5 more
doaj   +1 more source

Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis

Mediators of Inflammation, 2016
The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a challenge ...
Lang Yi, Mingju Hao, Tian Lu, Guigao Lin, Lida Chen, Ming Gao, Gaowei Fan, Dong Zhang, Guojing Wang, Xin Yang, Yulong Li, Kuo Zhang, Rui Zhang, Yanxi Han, Lunan Wang, Jinming Li   +15 more
doaj   +1 more source

High Prevalence of Penicillin-Nonsusceptible Streptococcus pneumoniae at a Community Hospital in Oklahoma

Emerging Infectious Diseases, 2000
During 1997, Oklahoma City's Hospital A reported penicillin-nonsusceptible Streptococcus pneumoniae in almost 67% of isolates. To confirm this finding, all Hospital A S.
Ronald L. Moolenaar, Ronda Pasley-Shaw, John R. Harkess, Anthony Lee, James M. Crutcher   +4 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1966
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1007/thumbnail ...

core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Assessment of utilization of automated systems and laboratory information management systems in clinical microbiology laboratories in Thailand.

PLoS ONE
IntroductionClinical microbiology laboratories are essential for diagnosing and monitoring antimicrobial resistance (AMR). Here, we assessed the systems involved in generating, managing and analyzing blood culture data in these laboratories in an upper ...
Preeyarach Klaytong, Panida Chamawan, Voranadda Srisuphan, Krittiya Tuamsuwan, Phairam Boonyarit, Adisak Sangchankoom, Archawin Rojanawiwat, Aekkawat Unahalekhaka, Kulsumpun Krobanan, Pimrata Leethongdee, Orapan Sripichai, Vanaporn Wuthiekanun, Paul Turner, Direk Limmathurotsakul   +13 more
doaj   +1 more source