Results 301 to 310 of about 5,568,953 (372)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Communicable diseases genomics network: promoting and harmonising pathogen genomics implementation for public health in Australia. [PDF]

Lancet Reg Health West Pac
Lin C, Jennison AV, Leong LEX, Speers DJ, Meumann EM, Cooley L, Kennedy K, Arnott A, Winter D, Rawlinson W, Robson J, Harris P, Donald A, Seemann T, Ballard SA, Kirk M, Sintchenko V, Williamson DA, Howden BP, Communicable Diseases Genomics Network.   +19 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Functional Characterization and a Real-World Clinical Laboratory Pilot of the Foundation for the National Institutes of Health Circulating Tumor DNA Quality Control Materials. [PDF]

JCO Precis Oncol
Paweletz CP, Forbes TD, Yee L, Heavey G, He HJ, He Z, Connors D, Stetson D, Keating S, Cole KD, Chen L, Pauly R, Bao H, Wu X, Pestano GA, Weaver AL, Kohli M, Hellwig S, Corner AS, Prantner AM, Wong SQ, Fox SB, Hewitt CA, Arnolda R, Jones GR, Craft J, McConechy M, Qahtani MA, Klemm F, Mohammad F, Sigman C, Liu LC, Gan Q, Konigshofer Y, Garlick R, Chin E, Kelloff G, Williams PM, McCormack R, Karlovich C.   +39 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Comparison of LC-MS methods for the quantitation of ciguatoxins in fish - A collaborative study. [PDF]

Food Chem X
Spielmeyer A, Hort V, Murray JS, Flores C, Sanchez-Henao A, Passfield EMF, Desbourdes C, Barreiro-Crespo L, Campàs M, Diogène J, Real Valcárcel F, Turquet J, Loeffler CR, Rambla-Alegre M.   +13 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Tracking Superbugs in the Digital Era.

J Med Internet Res
Basbouss-Serhal I.
europepmc   +1 more source

Optimizing resources in genomic surveillance: South Carolina's QC-plus approach. [PDF]

Front Public Health
Cox R, Goodwin G, Freeman J, Godfrey G, Kapingidza A, Smith A, Scott J, Diedhiou A, Buru K, Weaver CJ, Adair O, Meredith J, Aroh C.   +12 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source