Results 321 to 330 of about 5,568,953 (372)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Correction to: Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling. [PDF]

Cell Oncol (Dordr)
Pozios I, Seel NN, Hering NA, Hartmann L, Liu V, Camaj P, Müller MH, Lee LD, Bruns CJ, Kreis ME, Seeliger H.   +10 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

OASIS evaluation of the French laboratory diagnostic surveillance system: right people, right techniques but imperfect use. [PDF]

Front Vet Sci
Chikh M, Ngwa-Mbot D, Morignat E, Memeteau S, Amat JP.   +4 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Analytical validation of an immunoassay for the detection of <i>Cystoisospora</i> spp. coproantigen in canine and feline fecal samples. [PDF]

J Vet Diagn Invest
Porter AL, Hanna R, Saucier J, Florio H, Ferguson Q, Bezold T, Westra A, Smith P, Denis T, Buch J.   +9 more
europepmc   +1 more source

EndoCompass Project: Endocrine Laboratory Medicine.

Horm Res Paediatr
Heijboer AC, Hillebrand JJ, Keevil B, Ladang A, Davies E, Mertens J, Ozben T, Stankovic S, van Herwaarden AE, Raverot V.   +9 more
europepmc   +1 more source

Essential Safety Sheet in University Hospital and Healthcare Laboratories: A Comprehensive Evaluation Study with Longitudinal Impact Analysis. [PDF]

Healthcare (Basel)
Kwon OH, Sim GJ, Choi SH, Kim KY.
europepmc   +1 more source

Comparative Analysis of Detection Capabilities for Hepatitis B Antibody, Hepatitis C Antibody, and Syphilis Antibody in Different Medical Institutions in Kaifeng, China. [PDF]

Risk Manag Healthc Policy
Li H, Zhang Z, Li Q, Huang H, Ma CY.
europepmc   +1 more source

Strategies and challenges in containing antimicrobial resistance in East Africa: a focus on laboratory-based surveillance. [PDF]

Antimicrob Resist Infect Control
Molina A, Ihorimbere T, Nzoyikorera N, Nambozo EJ, Namubiru S, Nabadda S, Pimundu G, Githii SM, Nykwe GA, Abias AG, Msigwa FL, Ndagula R, Moremi N, Rwanyagatare F, Tuyishimire J, Mukankwiro T, Gahamanyi N, Mukagatare I, Lamshöft M, Nguinkal JA, Achol E, Lagu HI, Nzeyimana E, May J, Gehre F, Affara M.   +25 more
europepmc   +1 more source