Results 151 to 160 of about 11,639,456 (287)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Calcium Chemistry in Carbon-rich Circumstellar Environments: The Laboratory and Astronomical Discovery of Calcium Dicarbide, CaC₂ * [PDF]

H. M. Sen Gupta, P. Bryan Changala, J. Cernicharo, J. R. Pardo, M. Agúndez, C. Cabezas, B. Tercero, M. Guélin, Michael McCarthy   +8 more
openalex   +1 more source

Pathologists Overseas: A volunteer-based model for building sustainable, high-quality pathology and laboratory medicine services in low- and middle-income countries [PDF]

, 2022
Emily H. Glynn, Ann Marie Nelson, Merih Tesfazghi, Roa Harb, Timothy Amukele   +4 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Sequential biodegradation of 1,2,4-trichlorobenzene at oxic-anoxic groundwater interfaces in model laboratory columns

, 2020
Steven J. Chow, Michelle M. Lorah, Amar R. Wadhawan, Neal D. Durant, Edward J. Bouwer   +4 more
openalex   +2 more sources

Roofex® –Results of Laboratory Testing of a New Concept of Yieldable Tendon [PDF]

, 2007
François Charette, M Plouffe
openalex   +1 more source

Computer integrated laboratory testing [PDF]

The objective is the integration of computers into the Engineering Materials Science Laboratory course, where existing test equipment is not computerized. The first lab procedure is to demonstrate and produce a material phase change curve.
Dahl, Charles C.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Limits of agreement between measures obtained from standard laboratory and the point-of-care device Hemochron Signature Elite® during acute haemorrhage [PDF]

, 2013
Tobias Gauss, Sophie Hamada, Igor Jurcisin, Souhayl Dahmani, Larbi Boudaoud, Jean Mantz, Cathérine Paugam‐Burtz   +6 more
openalex   +1 more source

Epidemiological, clinical and laboratory aspects of Angiostrongylus cantonensis infection: an integrative review [PDF]

, 2022
M. S. N. Carvalho, Mellissa da Rocha Carvalho, J. A. O. Santos, H. B. G. Messias, Lucas Costa de Melo, Fernanda Helen Melo da Costa, João Pedro Fernandes de Carvalho, H. B. G. Messias, Saskya Araújo Fonseca, Mayara Andrade Souza, G. C. Ferreira-Júnior, Rodrigo Fonseca Lima, João Gomes da Costa, M. G. S. Cavalcanti, Thiago José Matos Rocha   +14 more
openalex   +1 more source