Results 151 to 160 of about 11,441,903 (299)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Pares y redes de laboratorios del Centre National de la Recherche Scientifique y de sus asociados.
The paper addresses irreversible cooperation in research partnerships. It analyzes longitudinal data from various contracts signed by research units of the French National Centre for Scientific Research (CNRS), and companies or public organizations.
Pierre Bès, Marie +2 more
doaj
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]
Song S, Du H, Lu X, Luo B, Li Z.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Establishment of a Purge and Trap Continuous-Flow Isotope Ratio Mass Spectrometer System for Analysis of Stable Nitrate Isotopes (δ<sup>15</sup>N and δ<sup>18</sup>O) in Water Samples by Ti(III) Reduction. [PDF]
Gcakasi MN, Stumpp C, Watzinger A.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Problem-Based Learning (PBL) Model in Teaching Medical Laboratory Science at University of Hawai'i. [PDF]
Nxedhlana V.
europepmc +1 more source

