Results 151 to 160 of about 7,625,703 (311)

Annual Report - Marine Biological Laboratory, 1939

open access: yes, 1940
Annual report of the Marine Biological Laboratory in Woods Hole. 1939.
Marine Biological Laboratory (Woods Hole MA)
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1984

open access: yes, 1985
Annual report of the Marine Biological Laboratory in Woods Hole. 1984.
Marine Biological Laboratory (Woods Hole MA)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1981

open access: yes, 1982
Annual report of the Marine Biological Laboratory in Woods Hole. 1981.
Marine Biological Laboratory (Woods Hole MA)
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Pares y redes de laboratorios del Centre National de la Recherche Scientifique y de sus asociados.

open access: yesREDES: Revista Hispana para el Análisis de Redes Sociales, 2010
The paper addresses irreversible cooperation in research partnerships. It analyzes longitudinal data from various contracts signed by research units of the French National Centre for Scientific Research (CNRS), and companies or public organizations.
Pierre Bès, Marie   +2 more
doaj  

Annual Report - Marine Biological Laboratory, 1991

open access: yes, 1992
Annual report of the Marine Biological Laboratory in Woods Hole. 1991.
Marine Biological Laboratory (Woods Hole MA)
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1917

open access: yes, 1918
Annual report of the Marine Biological Laboratory in Woods Hole. 1917.
Marine Biological Laboratory (Woods Hole MA)
core  

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