Results 51 to 60 of about 11,441,903 (299)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Emergent Horizons in the Laboratory

open access: yes, 2010
The concept of a horizon known from general relativity describes the loss of causal connection and can be applied to non-gravitational scenarios such as out-of-equilibrium condensed-matter systems in the laboratory.
Barcelo C   +15 more
core   +1 more source

Does the Pedagogy for the Teaching of First Year Undergraduate Laboratory Practicals Still Meet the Needs of the Curriculum?

open access: yesIrish Journal of Academic Practice, 2014
This work examines the teaching approach for chemistry laboratory practicals for first year undergraduate students to determine if the underpinning pedagogical strategy meets the requirements for these students for the remainder of their undergraduate ...
Ann Hopper
doaj   +1 more source

Comparative assessment of absolute cardiovascular disease risk characterization from non-laboratory-based risk assessment in South African populations [PDF]

open access: yes, 2015
Background: All rigorous primary cardiovascular disease (CVD) prevention guidelines recommend absolute CVD risk scores to identify high- and low-risk patients, but laboratory testing can be impractical in low- and middle-income countries.
Gaziano, Thomas A   +12 more
core   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Biosafety Level 4 Laboratory User Training Program, China

open access: yesEmerging Infectious Diseases, 2019
Experienced, qualified personnel certified to work in high-level biocontainment laboratories contribute to the safe operation of these facilities.
Han Xia   +6 more
doaj   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

Can Labs Help With Vaccination? In Vitro Tests in Diagnosis of Allergy to COVID‐19 Vaccines–A Systematic Review

open access: yesImmunity, Inflammation and Disease
Introduction Since the outbreak of the coronavirus pandemic in 2019, vaccinations have proven to be a key strategy in disease prophylaxis. Although vaccines are safe from the perspective of the general population, hypersensitivity reactions have still ...
Jan Romantowski   +3 more
doaj   +1 more source

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