Results 41 to 50 of about 2,361,046 (293)

Diagnostic error reduction in the United States and Italy through the intervention of diagnostic management teams [PDF]

open access: yes, 2018
A major challenge to most countries is the growing cost of healthcare. The cost of laboratory testing is approximately 3% of the total clinical costs.
Adriana Berumen Velazquez   +2 more
core  

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Identification of the rs797045105 in the SERAC1 Gene by Whole-exome Sequencing in a Patient Suspicious of MEGDEL Syndrome

open access: yesBasic and Clinical Neuroscience, 2020
Introduction: Whole Exome Sequencing (WES) has been increasingly utilized in genetic determinants of various inherited diseases. Methods: We applied WES for a patient presenting 3-Methylglutaconic Aciduria (MEG), Deafness (D), Encephalopathy (E), and ...
Mina Zamani   +8 more
doaj  

Statistical Investigation of High Culture Contamination Rates in Mycobacteriology Laboratory

open access: yesFrontiers in Microbiology, 2022
BackgroundCulture of Mycobacterium tuberculosis remains the gold standard in mycobacteriology laboratories, constrained by the very high risk of contamination; therefore, contamination rate is an important key performance indicator (KPI) for laboratory ...
Muatsim Ahmed Mohammed Adam   +2 more
doaj   +1 more source

Humoral response in a patient with cutaneous nocardiosis [PDF]

open access: yes, 2000
The clinical appearance of infection due to Nocardia spp. varies widely. The law sensitivity of direct microscopy and the slow growth of the organism challenge the laboratory diagnosis.
Gandorfer, Arnd   +3 more
core   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou   +9 more
wiley   +1 more source

Implementation of a National Reference Laboratory for Buruli Ulcer Disease in Togo [PDF]

open access: yes, 2013
Background: In a previous study PCR analysis of clinical samples from suspected cases of Buruli ulcer disease (BUD) from Togo and external quality assurance (EQA) for local microscopy were conducted at an external reference laboratory in Germany.
Amekuse, Komi   +20 more
core   +3 more sources

Pancreas, Muscle, and Subcutaneous Fat Atrophy in Patients Undergoing Radiation for Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Radiation therapy (RT) is part of standard‐of‐care therapy in high‐risk neuroblastoma (HR‐NBL) but can significantly affect nearby tissue. The objectives of this study were (1) to characterize changes in pancreas volume after RT and (2) to characterize changes in body composition, including body weight percentile ...
Pradipta Debnath   +10 more
wiley   +1 more source

Etiology of vaginal/cervical discharge syndrome: Analysis of data from a referral laboratory in eastern India

open access: yesIndian Journal of Dermatology, 2018
Context: Sexually transmitted infections (STIs) and reproductive tract infections (RTIs) constitute important public health problem worldwide. Syndromic diagnosis of vaginal/cervical discharge (VCD) is often inaccurate leading to over- or under-treatment.
Ishita Ghosh   +4 more
doaj   +1 more source

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