Results 81 to 90 of about 2,361,046 (293)
Laboratory Diagnosis Of Sarcoidosis
Indian Journal of Dermatology, 2001 Sarcoidosis is not an uncommon disease. Unfortunately, the awareness amongst clinicians is lacking and due to overwhelming prevalence of tuberculosis, a disease with many similar features, the diagnosis is missed and often delayed.
Dutta S.K, Gupta S.K, Chattopadhyay A
doaj
A case of porphyria cutanea tarda in the setting of hepatitis C infection and tobacco usage [PDF]
, 2019 Porphyria cutanea tarda (PCT) is the most common type of porphyria, presenting in middle-aged patients with a photodistributed vesiculobullous eruption, milia, and scars.
Brinster, NK +4 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Optimization of the laboratory diagnosis of allergies with regard to regional peculiarities
Zdorovʹe Rebenka, 2015 Allergic pathology is one of the most pressing issues in contemporary medicine. The most important task during the treatment of allergic diseases is the determination of cause-significant allergens.
V.А. Кlymenko +2 more
doaj +1 more source
Interpretation of HRCT Scans in the Diagnosis of IPF: Improving Communication Between Pulmonologists and Radiologists. [PDF]
, 2018 Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease (ILD). In this review, we describe the central role of high-resolution computed tomography (HRCT) in the diagnosis of IPF and discuss how communication between ...
Chung, Jonathan H, Goldin, Jonathan G
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Laboratory diagnosis of Zika infection imported cases [PDF]
, 2016 O vírus Zika (Flavivirus) é um arbovírus transmitido sobretudo por mosquitos, mas também, por transmissão materno-fetal e sexual. Existem evidências que as infeções por vírus Zika podem estar associadas à síndrome de Guillian-Barré e a casos ...
Alves, Maria João, Zé-Zé, Líbia
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Epidemiological indicators for measles in the Odesa region
Aktualʹnaâ Infektologiâ, 2019 Background. In order to eliminate measles around the world, a panel of experts from the World Health Organization recommends increased attention be paid to improving the immunization system as a whole, to carry out early detection of infections, to ...
V.O. Goncharov +4 more
doaj +1 more source
Spinal stenosis: A summary and review [PDF]
, 1993 A review of the etiology, clinical, radiological and laboratory presentation, differential diagnosis and management of spinal stenosis is presented.
Walker, B.F.
core +1 more source