Results 91 to 100 of about 7,738,195 (314)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Oak Ridge National Laboratory Report ORNL-2518

open access: yes, 1958
Report issued by the Oak Ridge National Laboratory displaying a single chart showing measurements of the gamma-ray, fast-neutron, and thermal-neutron dose ...
Oak Ridge National Laboratory
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

University of California Radiation Laboratory Report UCRL-923

open access: yes, 1950
Quarterly progress report on various research projects conducted at the University of California Radiation ...
Lawrence Berkeley National Laboratory
core  

Annual Report - Marine Biological Laboratory, 2013 [PDF]

open access: yes, 2011
Annual report of the Marine Biological Laboratory in Woods Hole. 2013. Includes lists of students, faculty, and researchers.Published in two parts. Printed document includes message from the President & Director, highlights, MBL at-a-glance, finanicals,
Marine Biological Laboratory (Woods Hole MA)
core  

Induction of HIV-Specific T Cell Responses Using αDC1 Pulsed With Conserved HIV-1 Peptides

open access: yesJournal of Immunology Research
Despite the effectiveness of antiretroviral therapy (ART) in suppressing HIV-1 replication and reducing morbidity, viral eradication remains unachievable due to the persistence of latent reservoirs, particularly within memory CD4+ T cells. Dendritic cell
Laís Teodoro Da Silva   +13 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1895

open access: yes, 1896
Annual report of the Marine Biological Laboratory in Woods Hole. 1895.
Marine Biological Laboratory (Woods Hole MA)
core  

An Investigation on the State of Taking Experimental Animals as Subjects in Nursing Research

open access: yesHuli yanjiu, 2004
Objective: to find out the basic state of taking experimental animals as subjects in nursing scientific research in China. Method: articles of taking experimental animals as subjects of 6 periodicals had been published from 1994 to 2002 were reviewed and
杨小平, 王惠珍
doaj  

Effects of Injectable Solutions on the Quality of Monocyte-Derived Dendritic Cells for Immunotherapy

open access: yesJournal of Immunology Research
Therapeutic vaccines based on monocyte-derived dendritic cells have been shown to be promising strategies and may act as complementary treatments for viral infections, cancers, and, more recently, autoimmune diseases.
Laís Teodoro Da Silva   +8 more
doaj   +1 more source

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