Results 131 to 140 of about 20,315,662 (409)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Investigation of friction hysteresis using a laboratory-scale tribometer [PDF]

open access: yes, 2011
The current paper addresses the characterization of dynamic friction by using a laboratory-scale tribometer. A special post-processing script in MatLab has been developed in order to analyse the data from the experiments.
De Baets, Patrick   +3 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Laboratory hard X-ray photoelectron spectroscopy of La$_{1-x}$Sr$_{x}$MnO$_{3}$

open access: yes, 2015
A laboratory hard X-ray photoelectron spectroscopy (HXPS) system equipped with a monochromatic Cr K$\alpha$ ($h\nu = 5414.7$ eV) X-ray source was applied to an investigation of the core-level electronic structure of La$_{1-x}$Sr$_x$MnO$_3$.
Hishida, Tomoko   +7 more
core   +1 more source

Age-related differences in Rostral-Middle locus coeruleus microstructure: A critical role in cognitive decline revealed by magnetic resonance relaxometry

open access: yesAlzheimer’s Research & Therapy
Background The Locus Coeruleus (LC) is a critical brain region affected by neurodegenerative diseases and aging. Despite its importance, in-vivo investigations of age-related LC degeneration and association with cognitive decline have been limited ...
Jonghyun Bae   +11 more
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Model investigation of inlet plenum flow straightening techniques for altitude test facility [PDF]

open access: yes
An investigation was conducted to evaluate and improve the quality of the airflow to be supplied to the engine in altitude test chambers 3 and 4 of the Propulsion Systems Laboratory at the Lewis Research Center.
Linke, H. G., Riddlebaugh, S. M.
core   +1 more source

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