Exoscope and operative microscope for training in microneurosurgery: A laboratory investigation on a model of cranial approach. [PDF]
Front Surg, 2023 Calloni T +7 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A regression technique for evaluation and quantification for water quality parameters from remote sensing data [PDF]
The objective of this paper is to define optical physics and/or environmental conditions under which the linear multiple-regression should be applicable.
Kuo, C. Y., Whitlock, C. H.
core +1 more source
Bronchopneumonia with interstitial pneumonia in beef feedlot cattle: Characterization and laboratory investigation. [PDF]
Vet Pathol, 2023 Haydock LAJ +6 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Photogrammetric technique for in-flight ranging of trailing vortices using entrained balloons [PDF]
A method for experimentally determining the radial distance of a probe aircraft from a trailing vortex is described. The method relies on photogrammetric triangulation of targets entrained in the vortex core.
Burner, Alpheus W. +2 more
core +1 more source
Laboratory Investigation of Storage Stability and Aging Resistance of Slightly SBS-Modified Bitumen Binders. [PDF]
Materials (Basel), 2023 Yu H, Mo L, Zhang Y, Qi C, Wang Y, Li X.
europepmc +1 more source