Results 151 to 160 of about 20,315,662 (409)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Group-IV graphene- and graphane-like nanosheets

, 2011
We performed a first principles investigation on the structural and electronic properties of group-IV (C, SiC, Si, Ge, and Sn) graphene-like sheets in flat and buckled configurations and the respective hydrogenated or fluorinated graphane-like ones.
Bekaroglu E., Boukhvalov D. W., Cahangirov S., Casolo S., Castro Neto A. H., Charlier J. C., Denille B. de Lima, Elias D. C., Garcia J. C., Garcia J. C., Geim A. K., Geim A. K., Houssa M., Huda M. N., Joelson C. Garcia, João F. Justo, Kresse G., Kresse G., Leenaerts O., Lucy V. C. Assali, Monkhorst H. J., Nakano H., Novoselov K. S., Perdew J. P., Popok V. N., Pumera M., Schwierz F., Sofo J. O., Tang S. B., Topsakal M., Voon L. C. L. Y., Wang G. X., Yin M. T., Zhang Y., Zhang Y. B.   +34 more
core   +1 more source

Development of swimming speed-based biomarker reveals interactive toxicity of TCEP and TCPP in amphibian larvae

Ecotoxicology and Environmental Safety
Tris(2-chloroethyl) phosphate (TCEP) and tris(2-chloro-1-methylethyl) phosphate (TCPP) are increasingly co-detected in various aquatic environments, yet their combined toxicity remains poorly understood.
Xin-Dan Cao, Zi-Ying Wang, Wen-Qi Xie, Jia-Jun Hao, Yi-Ge Xie, Zi-Yong Xiang, Guo-Hua Ding   +6 more
doaj   +1 more source

Laboratory Investigation of Nanofluid-Assisted Polymer Flooding in Carbonate Reservoirs. [PDF]

Nanomaterials (Basel), 2022
Ulasbek K, Hashmet MR, Pourafshary P, Muneer R.   +3 more
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Studies of highway skew slab-bridges with curbs. A report of an investigation conducted by the Engineering Experiment Station, University of Illinois, [PDF]

On t.p. of v. 2: A report of an investigation conducted by the Engineering Experiment Station, University of Illinois, in cooperation with the Bureau of Public Roads, U. S. Dept. of Commerce and the Division of Highways, State of Illinois.Bibliographical
Allen, John Winfield, Jensen, Vernon Peter   +1 more
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Bronchopneumonia with interstitial pneumonia in beef feedlot cattle: Characterization and laboratory investigation. [PDF]

Vet Pathol, 2023
Haydock LAJ, Fenton RK, Sergejewich L, Veldhuizen RAW, Smerek D, Ojkic D, Caswell JL.   +6 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick, Centers for Disease Control and Prevention (CDC), Clayton, Anna, Feikin, Daniel, Glaser, Carol, Harriman, Kathleen, Nix, William Allan, Padilla, Tasha, Pan, Chao, Reichel, John, Sejvar, James, Sheriff, Heather, Van Haren, Keith, Waldron, Paul, Watt, James, Waubant, Emmanuelle, Yagi, Shigeo, Yen, Cynthia   +17 more
core   +1 more source