Results 51 to 60 of about 20,315,662 (409)

An Experimental Study of Emission and Combustion Characteristics of Marine Diesel Engine with Fuel Injector Malfunctions

Polish Maritime Research, 2016
The presented paper shows the results of the laboratory study on the relation between chosen malfunctions of a fuel injector and composition of exhaust gas from the marine engine.
Kowalski Jerzy
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Host defence peptide LEAP2 contributes to antimicrobial activity in a mustache toad (Leptobrachium liui)

BMC Veterinary Research, 2023
Background The liver-expressed antimicrobial peptide 2 (LEAP2) is essential in host immunity against harmful pathogens and is only known to act as an extracellular modulator to regulate embryonic development in amphibians.
Jie Chen, Chi-Ying Zhang, Jing-Yi Chen, Rachel Wan Xin Seah, Le Zhang, Li Ma, Guo-Hua Ding   +6 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling

Cell Death and Disease, 2020
Cannabinoid 1 receptor (CB1R) expression is upregulated in the liver with viral hepatitis, cirrhosis, and both alcoholic and non-alcoholic fatty liver disease (FLD), whereas its expression is muted under usual physiological conditions.
Yoo Kim, Sudeep Gautam, Kanikkai Raja Aseer, Jaekwan Kim, Prabha Chandrasekaran, Caio Henrique Mazucanti, Paritosh Ghosh, Jennifer F. O’Connell, Máire E. Doyle, Ashley Appleton, Elin Lehrmann, Qing-Rong Liu, Josephine M. Egan   +12 more
doaj   +1 more source

Lean regional muscle volume estimates using explanatory bioelectrical models in healthy subjects and patients with muscle wasting

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background The availability of non‐invasive, accessible, and reliable methods for estimating regional skeletal muscle volume is paramount in conditions involving primary and/or secondary muscle wasting.
Damien Bachasson, Alper Carras Ayaz, Jessie Mosso, Aurélie Canal, Jean‐Marc Boisserie, Ericky C.A. Araujo, Olivier Benveniste, Harmen Reyngoudt, Benjamin Marty, Pierre G. Carlier, Jean‐Yves Hogrel   +10 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Prognostic value of TERF1 expression in prostate cancer

Journal of the Egyptian National Cancer Institute, 2021
Background Telomere dysfunction is one of the hallmarks of cancer and is crucial to prostate carcinogenesis. TERF1 is a gene essential to telomere maintenance, and its dysfunction has already been associates with several cancers. TERF1 is a target of miR-
Gabriel Arantes dos Santos, Nayara Izabel Viana, Ruan Pimenta, Vanessa Ribeiro Guimarães, Juliana Alves de Camargo, Poliana Romão, Sabrina T. Reis, Katia Ramos Moreira Leite, Miguel Srougi   +8 more
doaj   +1 more source

Laboratory Investigation of Dyslipidemia [PDF]

Laboratory Medicine, 1998
Cardiovascular disease is the leading cause of illness and death in the United States. Disorders of lipid and lipoprotein metabolism (dyslipidemia) predispose patients to premature atherosclerosis. Dyslipidemias can be classified as hypercholesterolemia, hypertriglyceridemia, combined hyperlipidemia, and low levels of high-density lipoprotein ...
Ishwarlal Jialal, Sridevi Devara
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source