Results 61 to 70 of about 20,315,662 (409)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Case report of neurobrucellosis: a rare complication and neuroimaging findings of a common disease

Frontiers in Immunology
Background and objectiveNeurobrucellosis is a rare neurological disorder characterized by diverse clinical manifestations. Although several relevant cases were reported, our understanding of this disorder is limited.
Yu Zhang, Yu Zhang, Xiao-Yi Zou, Xiao-Yi Zou, Ling Liu   +4 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Retrospective study on occurrence of bovine gastrointestinal parasitic infections in different regions of Haryana

Indian Journal of Animal Sciences
The production and reproduction of livestock is hampered by the presence of gastrointestinal (GI) parasitic infections. The effect of parasites ranges from anorexia, loss of body condition, anaemia, diarrhoea, protein losing enteropathy and loss of body
ANAND PRAKASH, VANDNA BHANOT, RAHUL YADAV, PANKAJ KUMAR   +3 more
doaj   +1 more source

The complete mitochondrial DNA for the Fujian Bamboo-leaf Frog Odorrana exiliversabilis (Anura: Ranidae) by next-generation sequencing

Mitochondrial DNA. Part B. Resources, 2021
The complete mitochondrial DNA (mtDNA) for Odorrana exiliversabilisLi, Ye and Fei 2001 (Anura: Ranidae) was determined in this study. The length of complete mtDNA was 17,122 bp, including 13 PCGs (COI-III, ND1-6, ND4L, ATP6, ATP8 and CYTB), 25 tRNA genes,
Jun-Jie Zhong, Li Ma, Zhi-Hua Lin, Guo-Hua Ding, Si-Te Luo   +4 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Foodborne outbreaks laboratory investigation, 2015 [PDF]

, 2016
O Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA), em parceria com a Direção-Geral de Alimentação e Veterinária (DGAV), notifica anualmente à European Food Safety Authority (EFSA) os dados dos surtos de toxinfeção alimentar ocorridos em ...
Barreira, Maria João, Bonito, Conceição Costa, Calhau, Maria Antónia, Coelho, Anabela, Correia, Cristina Belo, Cunha, Isabel Campos, Flores, Cristina, Furtado, Rosália, Lopes, Teresa Teixeira, Machado, Jorge, Maia, Carla, Marcos, Silvia, Moura, Isabel Bastos, Pena, Cláudia, Santos, Susana, Saraiva, Margarida, Silveira, Leonor, Sousa, Isabel, Toscano, Maria Manuel, Viegas, Silvia   +19 more
core  

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Physical activity and sedentary behaviour of adolescents and their parents: a specific analysis by sex and socioeconomic status

Archives of Public Health, 2023
Background The association of lifestyle habits of parents and of their children has been widely investigated as an important determinant for healthy habits in youth.
Eduardo Duarte de Lima Mesquita, William Rodrigues Tebar, Dayane Cristina Queiroz Correia, Juziane Teixeira Guica, Wésley Torres, Rômulo Araújo Fernandes, Ricardo Ribeiro Agostinete, Diego Giulliano Destro Christofaro   +7 more
doaj   +1 more source