Results 151 to 160 of about 18,259,704 (253)

Natural Compounds Targeting Coronary Microvascular Dysfunction: Mechanisms and Beyond

open access: yesDrug Design, Development and Therapy
Mingtai Chen,1– 3,* Xinyi Xiang,4,* Xinrui Yang,5,* Youyou Fu,5 Zhenxun Wan,5 Shiyun Yang,5 Qiuyu Liu,6 Gang Luo,5 Mengnan Liu5 1Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen ...
Chen M   +8 more
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Pathology laboratory, 1914

open access: yes, 1914
This glass lantern slide features a black and white photograph of the pathology laboratory of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Human Gallbladder Cancer Organoids. [PDF]

open access: yesCell Prolif
Xiang D   +37 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Author Correction: CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis. [PDF]

open access: yesNat Commun
Cui H   +15 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Short and Medium Chain Fatty Acids in a Cohort of Naïve Multiple Sclerosis Patients: Pre- and Post-Interferon Beta Treatment Assessment

open access: yesBiologics: Targets & Therapy
Laura Barcutean,1,2 Lenard Farczadi,3 Ion-Bogdan Manescu,4 Silvia Imre,3,5 Smaranda Maier,1,2 Rodica Balasa1,2 1Department of Neurology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, 540142 ...
Barcutean L   +5 more
doaj  

Molecular insights into Candida auris glycosylphosphatidylinositol transamidase. [PDF]

open access: yesProtein Cell
Ding X   +12 more
europepmc   +1 more source

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