Results 81 to 90 of about 3,368,001 (282)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

NH Department of Helath and Human Services Public Health Laboratories Shellfish Program Activites January 2006 – December 2006 [PDF]

, 2007
The Department of Health and Human Services-New Hampshire Public Health Laboratories (DHHS-NHPHL) has continued to carry out various actions providing laboratory analyses for the routine water quality monitoring, “Red Tide” monitoring, and additional ...
Wikoff, Peter C
core   +2 more sources

The analysis of a long-term experience of studying inactivated cell-culture vaccines for preventing tick-borne encephalitis of domestic and foreign manufacture in terms of specific activity (immunogenicity)

Биопрепараты: Профилактика, диагностика, лечение, 2018
The analysis of the use of the method for the evaluation of specific (immunogenic) activity of vaccines for preventing tick-borne encephalitis (TBE vaccines) against protective dilution (PD50) and the minimum immunizing dose (MID50) has been performed ...
M. S. Vorobieva, O. S. Afonina, O. A. Barhaleva, M. S. Shcherbinina, K. A. Sarkisyan, A. V. Rukavishnikov, V. A. Shevtsov, V. P. Bondarev   +7 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Load capacity of hardened gear wheels machined with cubic boron nitride (CBN) wedges

Metalurgija, 2013
The paper presents the results of exploitation examination of gear wheels with hardened bearing surface. The gears under investigation have been finish machined by the method elaborated by the author, with a tool possessing wedges made of CBN (cubic ...
R. Talar, A. Stoić
doaj  

Growth, Feed Utilization, Lipid Metabolism, and Metamorphosis of Bullfrog (Aquarana catesbeianus) Tadpoles Fed Diets With Different Lipid Levels

Aquaculture Nutrition
This study investigated the effect of dietary lipid levels on growth performance, lipid metabolism, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog (Aquarana catesbeianus) tadpoles.
Juan Gao, Ling Wang, Jian Zhang, Kangle Lu, Kai Song, Xueshan Li, Chunxiao Zhang   +6 more
doaj   +1 more source

Laboratory testing and model calibration of a crushed stone backfill in a geosynthetic reinforced soil wall [PDF]

E3S Web of Conferences
The objective of this study was to understand the effect of the choice of backfill constitutive models on the numerical simulation of a geosynthetic reinforced soil-integrated bridge system (GRS-IBS).
Okafor Chukwuma, Dunlop Sam, Anderson Brian, Montgomery Jack   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Laboratory testing of the communication based protection relays [PDF]

, 2015
The proper operation of control and protection applications in Substation Automation System (SAS) demands very high-speed and reliable communications that has being achieved by using IEC 61850.
Daboul, M., Wasserbauer, V.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source