Results 191 to 200 of about 24,309 (324)

Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway

Aging Cell, EarlyView.
Exercise improved PD pathology and memory by reducing microglial inflammation, apoptosis, and the formation of the NLRP3 inflammasome via irisin signaling. Irisin administration partially replicated the beneficial effects of exercise on PD pathology.
Renqing Zhao, Xin Tian, Haocheng Xu, Yuanxin Wang, Junjie Lin, Bin Wang   +5 more
wiley   +1 more source

The Blood-Labyrinth Barrier: Non-Invasive Delivery Strategies for Inner Ear Drug Delivery. [PDF]

Pharmaceutics
Yi Z, Wang X, Yin G, Sun Y.
europepmc   +1 more source

The Ethmoid Labyrinth, Point of Entry to Diseases of the Nasal Cavity, Paranasal Sinuses, the Orbit and Skull Base

Jan Bogataj, Ivana Tancer
openalex   +1 more source

Blood-Labyrinth Barrier Permeability in Menière Disease and Idiopathic Sudden Sensorineural Hearing Loss: Findings on Delayed Postcontrast 3D-FLAIR MRI [PDF]

, 2016
Michael N. Pakdaman, Gail Ishiyama, Akira Ishiyama, Kevin A. Peng, Grace Hyun J. Kim, Whitney B. Pope, Ali R. Sepahdari   +6 more
openalex   +1 more source

Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice

Aging Cell, EarlyView.
Li et al. revealed that aged gut microbiota induces cognitive decline and microglia‐mediated synapse loss. Fecal Bifidobacterium pseudolongum abundance was reduced in patients with cognitive impairment and microbiota transplantation from patients with fewer B.p abundance yielded worse cognitive behavior in mice.
Mingxiao Li, Jiaoqi Ren, Yiyang Bao, Wenjing Wei, Xuefei Yu, Xiaofang He, Mutalifu gulisima, Lili Sheng, Ningning Zheng, Jianbo Wan, Houguang Zhou, Ling Zhao, Houkai Li   +12 more
wiley   +1 more source

The pathological characteristics of enzootic nasal adenocarcinoma in goats. [PDF]

J Vet Res
Li L, Wang Z, Qi W, Lv Y, Yao D.
europepmc   +1 more source

SGLT2 Inhibition by Enavogliflozin Significantly Reduces Aβ Pathology and Restores Cognitive Function via Upregulation of Microglial AMPK Signaling in 5XFAD Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
SGLT2 inhibition with Enavogliflozin significantly improves cognitive function and reduces Aβ pathology in the 5XFAD mouse model of Alzheimer's disease. Through AMPK activation, Enavogliflozin enhances microglial mitochondrial function and Aβ phagocytosis while reducing neuroinflammation.
Jihui Han, Jaehoon Song, Eun Sun Jung, Ji Won Choi, Hye Young Ji, Inhee Mook‐Jung   +5 more
wiley   +1 more source

Flight from the Fight? Civil War and its Effects on Refugees

, 2015
Civil war dominates conflict in the modern era. An effect of this is a large number of refugees, who flee from war-torn countries in favor of lands where they can live in safety.
Lowry, Paul D.
core  

Magnetic Vestibular Stimulation (MVS) As a Technique for Understanding the Normal and Diseased Labyrinth [PDF]

, 2017
Bryan K. Ward, Jorge Otero‐Millan, Prem Jareonsettasin, Michael C. Schubert, Dale Roberts, David S. Zee   +5 more
openalex   +1 more source

Accumulation of GSK‐3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission

Aging Cell, EarlyView.
Overexpression of GSK‐3β in DG GABAergic neurons impairs neurogenesis by reducing GABA release, which can be reversed by enhancing GABAergic transmission. ABSTRACT The activation of glycogen synthase kinase 3β (GSK‐3β) and the deterioration of spatial memory represent prominent pathological and clinical manifestations of Alzheimer's disease (AD ...
Fei Liu, Jiu‐Jing Cui, Xiao‐Lin Li, Zeng‐Min Zhang, Shao‐Hua Liang, Yi Sun, Jing‐Min Li, Hong‐Lin Qu, Jing Ye, Qi‐Peng Guo, Quan Zheng, Yong‐Feng Liu   +11 more
wiley   +1 more source