Results 271 to 280 of about 24,309 (324)

Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats

Experimental Physiology, EarlyView.
Abstract Obstructive sleep apnoea (OSA) is a prevalent cardiorespiratory disorder associated with significant neurocognitive consequences. Despite the higher prevalence of OSA in men, there is a strong association between OSA and Alzheimer's disease (AD), which disproportionately affects women.
Emily C. Cheung, Joan B. Escobar, Bridget R. Alber, Caitlin Ribeiro, Ishan Abdullah, Grant Kowalik, Jeannette Rodriguez, Grey Harral, Makeda Melkie, Aman Gill, John T. Ketzenberger, John Bethea, Vsevolod Y Polotsky, Vivek Jain, Kathryn Schunke, Matthew W. Kay, David Mendelowitz   +16 more
wiley   +1 more source

The paradox of healing. [PDF]

Pak J Med Sci
Khan SJ, Iftikhar M.
europepmc   +1 more source

Exercise promotes cognition and hippocampal mitochondrial complex II expression in female rats

Experimental Physiology, EarlyView.
ABSTRACT Evidence supports that exercise defends against age‐associated declines in brain health and protects against neurodegenerative disease. To help understand the molecular basis for the neuroprotection, we examined the impact of training on mitochondrial protein expression within the exercise–brain axis.
Zachary J. White, Keshari H. Sudasinghe, David C. Poole, Stephanie E. Hall   +3 more
wiley   +1 more source

Developing a Diagnostic Algorithm for Identifying Vestibular Neuronitis in Acute Dizziness: An Overview of Epidemiology, Pathogenesis, and Evidence-Based Guidelines for Diagnostic Approaches. [PDF]

Cureus
Vlastarakos PV, Sideris G, Vasileiou E, Michailidou E, Papadimitriou N, Palantzas D, Melissourgou K, Panagoulis E, Gogoulos PP, Nikolopoulos T.   +9 more
europepmc   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Mining and evaluation of adverse event signals for capmatinib based on the FAERS database. [PDF]

Front Pharmacol
Chen X, Jiang Y, Zhu H, Tian M.
europepmc   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

Safety of lifitegrast: A real-world pharmacovigilance study based on FAERS. [PDF]

PLoS One
Zhang C, Wang H, Chen X, Liu Y, Jiang P.
europepmc   +1 more source