Results 31 to 40 of about 18,433 (169)

LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB)

Signal Transduction and Targeted Therapy, 2022
Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide. However, the presence of the blood-labyrinth barrier (BLB) on the surface of the inner ear capillaries greatly hinders the effectiveness of ...
Xi Shi, Zihao Wang, Wei Ren, Long Chen, Cong Xu, Menghua Li, Shiyong Fan, Yuru Xu, Mengbing Chen, Fanjun Zheng, Wenyuan Zhang, Xinbo Zhou, Yue Zhang, Shiwei Qiu, Liyuan Wu, Peng Zhou, Xinze Lv, Tianyu Cui, Yuehua Qiao, Hui Zhao, Weiwei Guo, Wei Chen, Song Li, Wu Zhong, Jian Lin, Shiming Yang   +25 more
doaj   +1 more source

3D Model to Understand the Diagnosis and Treatment of Horizontal Canal BPPV

Turkish Archives of Otorhinolaryngology, 2022
Objective:Our primary objective was to develop a three-dimensional (3D) model of the vestibular labyrinth to understand the pathophysiological mechanisms of benign paroxysmal positional vertigo (BPPV) observed during common diagnostic positional tests ...
Enis Alpin Güneri, Salim Hancı, Yüksel Olgun, Serpil Mungan Durankaya   +3 more
doaj   +1 more source

Recovery of Cochlear and Vestibular Function after Labyrinthine Haemorrhage

Acta Médica Portuguesa, 2014
Inner ear haemorrhage is a rare disorder with disabling symptoms. Prognosis is generally considered to be poor with essentially no chance of functional recovery. The most common aetiologies are related to blood dyscrasias, anticoagulant therapy or local
José Araújo-Martins, Patrícia Melo, Cristóvão Ribeiro, Ezequiel Barros   +3 more
doaj   +1 more source

The capture of circulating tumor cells by Labyrinth system as a tool for early stage lung cancer detection

Frontiers in Oncology
ObjectivesWe focus on utilizing the Labyrinth system for the detection of circulating tumor cells (CTCs) in patients with lung nodules. Our aim is to evaluate CTCs isolated through the Labyrinth system as a biomarker for early-stage lung cancer (LC ...
Peipei Jin, Peipei Jin, Hong Li, Mingran Xie, Jie Tang, Siming Zou, Ruiting Wang, Bin Yu, Tao Chen, Ju Zhang, Ju Zhang   +10 more
doaj   +1 more source

Unlocking the Power of Exosomes for Crossing Biological Barriers in Drug Delivery

Pharmaceutics, 2021
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup of nanovesicles called exosomes has been driving the research field to a new regime for understanding cellular communication.
Rebekah Omarkhail Elliott, Mei He
doaj   +1 more source

Labyrinthectomy and Vestibular Neurectomy for Intractable Vertiginous Symptoms

International Archives of Otorhinolaryngology, 2017
Introduction Labyrinthectomy and vestibular neurectomy are considered the surgical procedures with the highest possibility of controlling medically untreatable incapacitating vertigo.
Alfredo Vega Alarcón, Lourdes Olivia Vales Hidalgo, Rodrigo Jácome Arévalo, Marite Palma Diaz   +3 more
doaj   +1 more source

Avaliação e reabilitação vestibular no indivíduo idoso

Revista Brasileira de Geriatria e Gerontologia
Considerando a necessidade de propiciar melhora na qualidade de vida do idoso e a elevada incidência de queixas relacionadas aos transtornos de equilíbrio nessa faixa etária, este estudo teve como objetivo avaliar o equilíbrio estático e dinâmico de ...
Natália Daniela Rezende Mirallas, Marta Helena Souza De Conti, Alberto De Vitta, Ruy Laurenti, Sandra de Oliveira Saes   +4 more
doaj   +1 more source

Unlocking the secrets of aging: Epigenetic reader BRD4 as the target to combatting aging-related diseases

Journal of Advanced Research
Background: Aging, a complex and profound journey, leads us through a labyrinth of physiological and pathological transformations, rendering us increasingly susceptible to aging-related diseases.
Jiaxing Sun, Yu Gui, Shenghua Zhou, Xi-Long Zheng   +3 more
doaj   +1 more source

3D didactic model and useful guide of the semicircular conducts Modelo didático 3D e guia útil dos canais semicirculares

Brazilian Journal of Otorhinolaryngology, 2011
Knowledge of the anatomy and physiology of the semicircular canals and their central pathways is essential for the diagnosis of vestibular pathology.
Ricardo D'Albora Rivas
doaj   +1 more source

Navigating the labyrinth: Phenotypes of IgG4-related disease

Journal of Postgraduate Medicine
ABSTRACT We report a case of an elderly female with subacute submental neck swelling, dry cough, and a history of significant weight loss. Unexpectedly, a left submandibular chronic sialadenitis was noted on ultrasound of the neck, along with a thyroid nodule that, on biopsy, showed lymphocytic infiltration.
Shah, M, Bajan, K, Samant, R
openaire   +2 more sources