Results 71 to 80 of about 5,602 (197)

A De Novo Splicing Mutation of SRP72 in Bone Marrow Failure Syndrome Type 1: Case Report and Review of the Literature

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study reports a rare case of bone marrow failure syndrome type 1 (BMFS1) caused by a novel de novo splicing mutation (c.1502+1G>A) in the SRP72 gene. The 6‐year‐old patient presented with aplastic anemia and pancytopenia. Genetic analysis identified the mutation, which was absent in both parents, confirming its de novo origin.
Wang Xiangwen, Zhang Duo, Hao Wenjing, Hou Hui   +3 more
wiley   +1 more source

Potentielle Auswirkung der Genese der Schwerhörigkeit aud die subjektiv empfundene Lebensqualität [PDF]

, 2004
Die Pilotstudie der Hals-Nasen und Ohrenklinik der Universität Marburg hatte das Ziel den Einfluss der Ursache der Schwerhörigkeit auf die subjektiv empfundene Lebensqualität der Patienten genauer zu beleuchten.
Baitsch, Hendrik Alexander, Werner, J.A. Prof. Dr.   +1 more
core   +1 more source

Surgical Outcomes of Acute Mastoiditis in Pediatric Patients: A Pediatric Health Information System Study

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 1, Page 239-245, January 2026.
Abstract Objective To evaluate outcomes of surgically treated acute mastoiditis (AM) in pediatric patients using the Pediatric Health Information System (PHIS). Study Design Retrospective cohort study. Setting Pediatric tertiary care centers participating in the PHIS. Methods Children aged 0 to 18 years with AM treated from January 1, 2016, to December
Shachi Srivatsa, Brenna Rachwal, Taha Akbar, Nicholas Pennza, Lindsey Asti, Peter C. Minneci, Prashant Malhotra, Prasanth Pattisapu   +7 more
wiley   +1 more source

Gradenigo’s Syndrome and Labyrinthitis: Conservative versus Surgical Treatment

Case Reports in Otolaryngology, 2018
Background. Extracranial intratemporal complications of chronic suppurative otitis media (CSOM) are extremely rare. Gradenigo’s syndrome is defined as a clinical triad of otitis media, severe pain originating from the trigeminal nerve, and ipsilateral ...
Ahmad Al-juboori, Amira Nasser Al Hail
doaj   +1 more source

Impact of the COVID‐19 Pandemic on Cochlear Implant Usage in Children

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 1, Page 257-264, January 2026.
Abstract Objective To evaluate the impact of the COVID‐19 pandemic on cochlear implant (CI) usage in children by comparing hearing hour percentage (HHP) during the pandemic to prepandemic levels. Study Design Retrospective Cohort Study. Setting Primary Children's Hospital, Utah.
Peter Kfoury, Kathryn Tonkovich, Eun Kyung Jeon, Jordan C. Stout, Hannah Christensen, Megna D. Reddy, Matthew A. Firpo, Albert H. Park   +7 more
wiley   +1 more source

Cochlear turns measurements in patients with meningitis: A histopathological study

Laryngoscope Investigative Otolaryngology, 2020
Objective To demonstrate the cochlear turns area changes among patients with a history of meningitis, through otopatologic study. Methods We performed an analysis of the area of the bony cochlear turns and the cochlear lumen of the horizontal sections ...
Henrique F. Pauna, Michael M. Paparella, Sebahattin Cureoglu, Miguel A. Hyppolito   +3 more
doaj   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

Food Frontiers, Volume 6, Issue 6, Page 2554-2574, November 2025.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz, Ayesha Zahid, Hazrat Ismail, Misbah Ajaz   +3 more
wiley   +1 more source

Magnetic Resonance Imaging in Prediction of Sensorineural Hearing Loss in Patients with Neuroinfections

Journal of International Advanced Otology
BACKGROUND: Magnetic resonance imaging (MRI) may be useful in detecting labyrinthitis and thereby predicting the development of sensorineural hearing loss (SNHL) in adults with central nervous system (CNS) infections.
Frej Juul Vilhelmsen, Elisa Skovgaard Jensen, Bodil Damgaard, Per Cayé- Thomasen, Christian Thomas Brandt, Malene Kirchmann   +5 more
doaj   +1 more source

Neck pain and disability: A cross-sectional survey of the demographic and clinical characteristics of neck pain seen in a rheumatology clinic [PDF]

, 2004
This hospital-based cross-sectional cohort study examines the clinical and demographic features of neck pain, disability (using the Northwick Park neck pain questionnaire) and relationships to handicap in employment.
De Souza, LH, Frank, AO, Frank, CA
core   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

Advanced Science, Volume 12, Issue 38, October 13, 2025.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao, Xinyue Wang, Ming Liu, Xiao Fu, Nanfeng Zhang, Wenqing Yang, Junyi Ge, Yangyang Li, Duan Ma, Jing Ma, Weiping Wen, Dongdong Ren, Tianyu Zhang, Zhaoxu Tu   +13 more
wiley   +1 more source