Results 51 to 60 of about 4,936 (187)

Chronic Dry Eye Disease is Principally Mediated by Effector Memory Th17 Cells [PDF]

, 2014
Recent experimental and clinical data suggest that there is a link between dry eye disease (DED) and T cell-mediated immunity. However, whether these immune responses are a consequence or cause of ocular surface inflammation remains to be determined ...
Chauhan, Sunil K., Chen, Yihe, Dana, Reza, Lee, Hyun Soo, Saban, Daniel R.   +4 more
core   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Aquaporins: important but elusive drug targets. [PDF]

, 2014
The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water transport across the plasma membranes of cells in response to osmotic gradients.
A Bergamo, A Burykin, A Kimura, A Rossi, A Warth, A Warth, AB Chepelinsky, AJ Smith, AJ Yool, AJ Yool, Alan S. Verkman, AP Martins, AP Martins, AS Verkman, AS Verkman, B Bassarak, B Bertrand, B Ma, B Yang, B Yang, B Yang, B Yang, B Zhang, BC Kieseier, BJ Baum, BJ Baum, BJ Jin, BK Tamarappoo, BL de Groot, C Esteva-Font, C Goubau, C Maurel, CL Chou, CM Niemietz, D Fu, D Fu, D Seeliger, D Wesche, D Zhang, DC Blaydon, DG Bichet, DK Binder, DM Wingerchuk, E Beitz, E Lindahl, E Migliati, E Solenov, E Soupene, EM Muller, EM Nagy, ET Olesen, EW Miller, F Baumgart, FJ Detmers, G Di Giusto, G Fischer, G Soveral, G Soveral, GM Preston, GM Preston, GP Bienert, GP Nicchia, GT Manley, H Chen, H Hasegawa, H Sui, H Tsukaguchi, H Zhang, HJ Jung, HL Brooks, J Badaut, J Farinas, J Farinas, J Farinas, J Gao, J Hu, J Li, J Li, J Liu, J Palace, J Schnermann, JD Ho, JE Rash, JF Kun, JJ Iliff, JJ Irwin, JL Edelman, JM Crane, JP Morello, JR Thiagarajah, JS Hub, K Ishibashi, K Miranda, K Murata, K Oshio, K Oshio, K Oshio, KI Auguste, L Janosi, L Tradtrantip, L Tradtrantip, L Tradtrantip, L Tradtrantip, LJ Galietta, LM Holm, LS King, M Amiry-Moghaddam, M Araki, M Boone, M Dumas, M Endo, M Hara, M Hara-Chikuma, M Hara-Chikuma, M Hara-Chikuma, M Hara-Chikuma, M Herrera, M Kato, M Moore, M Ozu, M Ozu, Marc O. Anderson, Marios C. Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MG Mola, MH Levin, MH Levin, MJ Tait, MP Marrades, N Chihara, N Maeda, N Roudier, N Roudier, N Zhu, NN Haj-Yasein, O Bloch, O Bloch, P Padmawar, PM Deen, PW Phuan, R Gao, R Katada, R Musa-Aziz, R Zhang, RB Zhang, RI Macey, S Jelen, S Jelen, S Nielsen, S Nielsen, S Pavlovic-Djuranovic, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Sasaki, S Tornroth-Horsefield, SD Shields, SJ Wacker, SR Hinson, SR Hinson, T Gonen, T Hibuse, T Ma, T Ma, T Ma, T Ma, T Ma, T Yamamoto, T Zeuthen, TH Kwon, TL Pallone, V Berry, VA Lennon, VA Lennon, VJ Huber, VJ Huber, W Castro-Borges, X Cao, Y Liu, Y Morishita, Y Song, Y Song, Y Wang, YB Zhang, YH Huang, Z Zhang, ZH Li   +194 more
core   +1 more source

Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function

Aging Cell, Volume 25, Issue 2, February 2026.
In D‐galactose‐induced aging model, periodic therapeutic phlebotomy exerts significant and comprehensive anti‐aging effects by inducing bone marrow microenvironment restoration, which rebalances hematopoiesis to restore peripheral blood function and ameliorate systemic aging phenotypes.
Ji‐Ru Cai, Jian Zhang, Yue‐Xin Ning, Jing Zhang, Tian‐Ce Xu, Mei‐Chen Liu, Ke‐Xin Wang, Hui‐Sheng Chen   +7 more
wiley   +1 more source

Synergistic roles of aquaporin 5 and intra‐ and extracellular carbonic anhydrases in promoting CO2 diffusion across the Xenopus oocyte plasma membrane

The Journal of Physiology, Volume 604, Issue 3, Page 1174-1234, 1 February 2026.
Abstract figure legend Fick's law: JCO2=PM*,CO2±hAQP5·([CO2]os±bCA−[CO2]is±hCAII)TransmembraneCO2gradient${J}_{{\mathrm{CO}}_{2}}=\underset{\pm \mathrm{hAQP}5}{\underset{}{{P}_{\mathrm{M}^\ast ,{\mathrm{CO}}_{2}}}}\, \cdot \underset{\mathrm{Transmembrane}\ {\mathrm{CO}}_{2}\ \mathrm{gradient}}{\underset{}{(\underset{\pm \mathrm{bCA}}{\underset ...
Deng‐Ke Wang, Fraser J. Moss, Walter F. Boron   +2 more
wiley   +1 more source

Cisto ductal de glândula lacrimal em paciente com eritrodermia ictiosiforme congênita

Revista Brasileira de Oftalmologia
Resumo A ictiose lamelar é uma doença congênita de herança autossômica recessiva que se caracteriza clinicamente por descamação de toda a superfície corporal devido hiperceratose mucocutânea que pode levar a comprometimento oftalmológico.
Adriana Ribeiro de Almeida, Eduardo Damous Feijó   +1 more
doaj   +1 more source

Occlusion of retinal capillaries caused by glial cell proliferation in chronic ocular inflammation [PDF]

, 2015
The inner blood-retinal barrier is a gliovascular unit in which glial cells surround capillary endothelial cells and regulate retinal capillaries by paracrine interactions.
Artico, Marco, Bianchi, Enrica, Feher, Janos, Kovacs, Illés, Plateroti, Andrea Maria, Plateroti, Pasquale, Plateroti, Rocco, Ripandelli, Guido, Taurone, Samanta   +8 more
core   +2 more sources

Re‐evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract The present opinion deals with the re‐evaluation of sucralose (E 955) as food additive and with the safety of a proposed extension of use in food category (FC) 7.2 ‘Fine bakery wares’. Based on the available data, no safety concerns arose for genotoxicity of sucralose (E 955) and its impurities and degradation products.
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Monika Batke, Antonios Douros, James Chipman, Riccardo Crebelli, Peter Fürst, Thorhallur Halldorsson, Manuela Mirat, Alicja Mortensen, Matthew Wright, Oliver Lindtner, Stefania Barmaz, Consuelo Civitella, Zsuzsanna Horvath, Sara Levorato, Elena Mazzoli, Josef Daniel Rasinger, Ana Maria Rincon, Camilla Smeraldi, Alexandra Tard, Federica Lodi   +36 more
wiley   +1 more source

Tratamiento Quirúrgico de las interrupciones canaliculares Surgical treatment of canalicular disruptions

Revista Cubana de Oftalmología, 1999
Realizamos un estudio de 52 pacientes operados en nuestro centro con el diagnóstico de sección canalicular de urgencia o antigua durante un período de 5 años. Agrupamos a los pacientes de acuerdo con posibles agentes etiológicos, las técnicas quirúrgicas
Nereyda Martínez Suárez, Noelio Rodríguez Méndez   +1 more
doaj  

The Gene Encoding Human SCGB 2A1 is under Indirect Androgen Control Operating through an Sp Family Binding Site in Prostate Cells [PDF]

, 2003
The secretoglobins belong to a minority of proteins with unclear physiological function. In the past research in the field was dominated by work on the family founder member uteroglobin and its orthologs.
Professor Dr. Miguel Beato, Xiao, Fei
core   +1 more source