Results 1 to 10 of about 509,908 (294)

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. [PDF]

PLoS Genetics, 2017
The sequential use of signaling pathways is essential for the guidance of pluripotent progenitors into diverse cell fates. Here, we show that Shp2 exclusively mediates FGF but not PDGF signaling in the neural crest to control lacrimal gland development ...
Ankur Garg, Mukesh Bansal, Noriko Gotoh, Gen-Sheng Feng, Jian Zhong, Fen Wang, Ariana Kariminejad, Steven Brooks, Xin Zhang   +8 more
doaj   +11 more sources

Development of lacrimal gland organoids from iPSC derived multizonal ocular cells

Frontiers in Cell and Developmental Biology, 2023
Lacrimal gland plays a vital role in maintaining the health and function of the ocular surface. Dysfunction of the gland leads to disruption of ocular surface homeostasis and can lead to severe outcomes.
Melis Asal, Melis Asal, Gamze Koçak, Gamze Koçak, Vedat Sarı, Vedat Sarı, Tuba Reçber, Emirhan Nemutlu, Canan Aslı Utine, Canan Aslı Utine, Sinan Güven, Sinan Güven, Sinan Güven   +12 more
doaj   +2 more sources

DENERVATION OF THE LACRIMAL GLAND [PDF]

British Journal of Ophthalmology, 1958
THE surgical treatment of epiphora is now well established and on the whole satisfactory. A success rate of almost 90 per cent. can be expected for the operation of dacryocystorhinostomy (Stallard, 1950). There still remains a considerable number of cases where the puncta or canaliculi are strictured or absent, where the lacrimal sac is absent or ...
Jennifer L. Whitwell
openalex   +5 more sources

Amyloidosis of lacrimal gland

Indian Journal of Ophthalmology, 2009
Primary localized amyloidosis of lacrimal gland is a rare occurrence. This report describes a female patient with isolated amyloidosis of the lacrimal gland.
Prabhakaran Venkatesh, Babu Kalpana, Mahadevan Anitha, Murthy Sowmya   +3 more
doaj   +4 more sources

Advances in clinical examination of lacrimal gland [PDF]

Frontiers in Medicine, 2023
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou   +20 more
doaj   +2 more sources

Human Lacrimal Gland Gene Expression. [PDF]

PLoS ONE, 2017
The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease.
Vinay Kumar Aakalu, Sowmya Parameswaran, Mark Maienschein-Cline, Neil Bahroos, Dhara Shah, Marwan Ali, Subramanian Krishnakumar   +6 more
doaj   +2 more sources

Lacrimal gland choristomas

Arquivos Brasileiros de Oftalmologia, 2022
The purpose of this article was to report a case of intraconal lacrimal gland tissue and to review the literature on lacrimal gland choristoma. The magnetic resonance imaging findings of a biopsy-proven orbital case are also presented. A PubMed database search was performed using the key terms heterotopic, ectopic, aberrant, choristoma, and lacrimal ...
Cruz, Antonio Augusto V., Limongi, Roberto Murillo, Feijó, Eduardo Damous, Enz, Tim Jürg   +3 more
openaire   +7 more sources

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

npj Aging and Mechanisms of Disease, 2017
Regenerative medicine: lacrimal gland epithelium in vitro One possible approach to treat dry eye diseases is to transplant lacrimal glands generated in vitro from human embryonic stem cells into patients.
Masatoshi Hirayama, Shigeru B.H. Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K. Goparaju, Atsumi Soma, Yuhki Nakatake, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeto Shimmura, Kazuo Tsubota, Minoru S.H. Ko   +11 more
doaj   +2 more sources

Association of Intratumoral Microbiota with Prognosis in Patients with Lacrimal Gland Tumor [PDF]

Biomedicines
Background: While intratumoral microbiota have been identified in various cancers, their presence and clinical significance in lacrimal gland tumors remain largely unexplored.
Jianping Hu, Yidi Yang, Yiyi Feng, Yu Yu, Xin Song, Renbing Jia   +5 more
doaj   +2 more sources

A Ligation of the Lacrimal Excretory Duct in Mouse Induces Lacrimal Gland Inflammation with Proliferative Cells

Stem Cells International, 2017
The lacrimal gland secretes tear fluids to ocular surface, which plays an indispensable role in maintaining the health of the ocular epithelia and protecting the ocular surface from the external environment.
Ying Liu, Masatoshi Hirayama, Tetsuya Kawakita, Kazuo Tsubota   +3 more
doaj   +2 more sources