Results 341 to 350 of about 785,757 (422)

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

open access: yesCancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang   +6 more
wiley   +1 more source

Chemical Characterization of Alphitonia neocaledonica (Schltr.) Guillaumin Bark Extract and Its Anti‐Inflammatory Activities

open access: yesChemistry &Biodiversity, EarlyView.
Study of the anti‐inflammatory activities and chemical characterization of Alphitonia neocaledonica (Schltr.) Guillaumin bark extract. ABSTRACT Alphitonia neocaledonica (Schltr.) Guillaumin is a small forest tree endemic of New Caledonia traditionally used to treat rheumatic pain and dermatoses.
Karl Huet   +5 more
wiley   +1 more source

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

open access: yesChemBioChem, EarlyView.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann   +2 more
wiley   +1 more source

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